Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 311 for “"CRC"”.
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Oncogenic Kras and Telomere Biology In Crc Progression
<p>While colorectal cancer (CRC) patients diagnosed with localized stage disease (as defined by SEER) have a 5-year survival rate of 90%, this rate plunges to 14% for patients diagnosed with metastatic CRC. Consequently, there is an immediate imperative to elucidate the mechanisms that drive the …
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ROLE OF CRC IN THE REGULATION OF ALGINATE IN PSEUDOMONAS AERUGINOSA
… that the catabolic repression control (Crc) protein repressor may affect alginate gene expression. A putative Crc binding site was observed adjacent to the ribosome binding site of algD, the first gene in the 12-gene alginate biosynthetic operon. We hypothesized that Crc binding here …
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The effect of RAN inhibition on human colorectal cancer cells (CRC)
Colorectal cancer (CRC) is the third most widespread and fourth most fatal malignancy disease. The CRC from a primary site can spread to other tissues, forming secondary tumours. CRC can metastasise to the liver through the effect of K-Ras and Pten mutation (Mt.) (Abbas et al. 2020). This study …
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The regulatory roles of PyrR and Crc in pyrimidine metabolism in Pseudomonas aeruginosa
… that the catabolite repression control (Crc) protein was indirectly involved in pyr gene regulation, and shown to negatively regulate expression of PyrR at the posttranscriptional level.
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Analysis of the involvement of exosomal miRNAs and proteins in the response of CRC cells to Cetuximab
Recentemente è stata dimostrata l’importanza della comunicazione intercellulare attraverso vescicole rilasciate dalle cellule sia a livello fisiologico sia a livello dello sviluppo e della progressione dei tumori, compresi l’angiogenesi ed i processi metastatici. La comunicazione cellulare può …
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Aproximación a la optimización en la planeación y gestión en organizaciones públicas bajo la Teoría de Restricciones (TOC) - caso de estudio - CRC
… y de su aplicación al caso particular de la CRC, entidad pública a cargo de la regulación sectorial de las Tecnologías de la Información y las Comunicaciones en Colombia.
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An examination of the use of endoscopy screening tests for colorectal cancer among African American medicare beneficiaries in the northwest region of Louisiana
… and die from late-stage colorectal cancer (CRC) than other US population groups (ACS, 2011a). This specific disparity persists even though CRC deaths can be reduced by as much as 60% through screening (CDC, 2011c). Health or CRC disparities are not new phenomena, but the causes and …
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Trends in Premature Mortality from Colorectal Cancer in the United States, 2000 to 2010
<p>Differences in colorectal cancer (CRC) incidence and mortality exist between men and women, different racial and ethnic groups, and geographical loci. However, little is known about the extent of premature death from CRC. This study investigates premature mortality as measured in years of …
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RELATIONSHIPS BETWEEN MASCULINITY BELIEFS AND COLORECTAL CANCER SCREENING IN MALE VETERANS
Colorectal cancer (CRC) is the third most common cancer diagnosed and the third most common cause of cancer deaths among men in the United States. Although CRC screening tests can reduce CRC incidence and mortality, men’s current rates of CRC screening fall below screening objectives. Results from …
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Modeling Racial Differences in Colorectal Cancer Screening: Evidence from a Nationally Representative Sample
… evidence that screening for Colorectal cancer (CRC) can reduce cancer incidence and mortality, screening adherence remains low. Racial differences in CRC incidence and mortality are well documented in the literature. Racial differences in CRC screening use remain mixed with most studies using …
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Impact of Diabetes on Colorectal Cancer Outcomes
… chronic comorbid condition seen in elderly CRC patients. Outcomes of CRC patients with diabetes specifically stage at diagnosis, emergency condition for CRC surgery, survival, and mortality have been insufficiently explored. The aims of the study were to investigate the association between …
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Inflammatory Biomarkers, Genetics, and Survival among Colorectal Cancer Patients
… increases the risk of colorectal cancer (CRC) through inflammation-mediated mechanisms. Current evidence regarding the connection between circulating inflammatory biomarkers and CRC prognosis is limited to C-reactive protein (CRP) and interleukin (IL)-6. However, other inflammatory …
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Beliefs about Diet and Colorectal Cancer Prevention in an Urban Population
… best immediate strategy for colorectal cancer (CRC) prevention, but studies also indicate changes in diet can lower risk of developing CRC. Forty-five percent of CRC cases have been estimated preventable through appropriate diet, physical activity and weight management. Despite evidence on the …
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Epidemiological evidence that can help to improve timely diagnosis of colorectal cancer in New Zealand.
Incidence rates of colorectal cancer (CRC) in New Zealand (NZ) are among the highest in the world. The long-term survival rates in NZ are poor, which has partially been attributed to late diagnosis. Considering that CRC is a curable disease if diagnosed early, conducting research targeted at the …
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Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer
Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. Accumulating epidemiological evidence suggests …
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Rights of children in criminal proceedings : a comparative analysis on the compatibility of the Malaysian juvenile justice system with the standards of the Convention on Rights of Children (CRC)
… United Nations Convention on Rights of Children (CRC), which was adopted on 20th November 1989, has laid down international standards and legal framework on rights of children under juvenile justice. The CRC’s standards on this matter have served as a useful guideline and benchmark to state …
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Development of solid lipid nanoparticles for sustained release of anticancer agents
… of the anticancer drug substance curcumin (CRC), have been investigated. The physicochemical characteristics of the CRC-SLNs were investigated by particle size, zeta potential and stability measurements. In addition transmission electron microscopy was used to study the morphology of the …
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Orthotopic liver metastasis mouse models of mismatch repair-proficient colorectal cancer recapitulate clinical inefficacy of immune checkpoint blockade
… of mortality in patients with colorectal cancer (CRC). Immune checkpoint blockade (ICB) therapy has significantly improved overall survival in several cancer types including melanoma and non-small cell lung cancer. However, patients with mismatch repair-proficient (pMMR) metastatic CRC do not …
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Hamming distance as a metric for the detection of side channel in 802.11 wireless communications
… by using a different Cyclic Redundancy Check (CRC) polynomial in order to create a side channel. Malicious nodes exploit the fact that normal unsuspecting nodes will immediately drop erroneous frames. A metric called the Hamming Distance (HD) was proposed for detection which distinguishes …
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Modulation of Pi3K-Akt Pathway In Colorectal Cancer
… is activated in 20-40% colorectal cancers (CRC) through PTEN loss (PTEN<sup>loss</sup>) and <em>PIK3CA</em> mutations (<em>PIK3CA</em><sup>mut</sup>). Allosteric AKT inhibition with MK2206 monotherapy has been ineffective in CRC patients. We investigated the impact of MK2206 on …
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