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Showing 1 to 1 of 1 for “"CPXV203"”.
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Structural Mechanism of Orthopoxvirus Sabotage of MHCI Antigen Presentation
… two ER-resident MHCI saboteurs: CPXV012 and CPXV203). CPXV012 inhibits peptide loading of MHCI within the peptide-loading complex: PLC), while CPXV203 inhibits surface expression of both murine and human MHCI through the use of a C-terminal ER-retention sequence: KTEL). An association: direct …