Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CPVT"”.
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The Binding Properties and Functional Consequences of Ryr2-Cam Interaction
… in HF and lethal arrhythmias, such as CPVT. And DPc10 can bind to RyR2 and recapitulate this arrhythmogenic RyR2 leakiness by unzipping N- and central-domains. In this study fluorescently-labeled DPc10, FKBP12.6, and CaM were used to characterize the binding properties of DPc10 to RyR2 …
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DEVELOPMENT OF AN IN VIVO MULTITASKING BIOLUMINESCENT REPORTER GENE PLATFORM FOR THE PRECLINICAL EVALUATION OF RNA THERAPEUTICS
… polymorphic ventricular tachycardia (CPVT). Using multiple murine and human cell models, the effects of the siRNA and its calcium phosphate nanoparticle formulation were systematically evaluated across inflammatory, Th2 immune response, oxidative stress, and proliferative pathways. …