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Showing 1 to 3 of 3 for “"CPSF6"”.
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The Role of Cleavage and Polyadenylation Spcific Factor 6 (CPSF6) in Hematopoiesis
… and polyadenylation specific factor 6 (<em>Cpsf6</em>) translocation is frequently reported in APLL, which is Acute Promyelocytic Leukemia (APL)-like acute myeloid leukemia (AML) and other types of blood diseases associated with abnormal hematopoiesis. CPSF6 is a subunit of the Cleavage …
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Differential modulation of HIV-1 capsid uncoating kinetics revealed by a novel single-particle uncoating assay
… CANTD-CTD hexameric interface, such as PF74 and CPSF6p, accelerate or do not alter capsid opening but strongly stabilise the remaining lattice. In contrast, binding of polyanions to the central capsid pore, such as hexacarboxybenzene and the newly discovered CA-binders IP6 and ATP, strongly delay …
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Engineering fluorescent imaging platforms to characterise molecular interactions with HIV-1 capsid
… polyadenylation specificity factor subunit 6 (CPSF6) expressed as a full-length protein in a cell-free expression system suggested a role of oligomerisation to enhance binding via avidity. In the second approach, the biosensor surface was modified with cross-linked CA spheres as an alternative …