Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"CPSF"”.
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In vitro reconstitution of the human pre-mRNA 3′ end processing machinery and mechanistic insights into endonuclease activation
… cleavage and polyadenylation specificity factor (CPSF; CPF in yeast). The polyadenylation activity of CPSF has been studied in detail biochemically, but our understanding of how CPSF cleaves the pre-mRNA remains limited. CPSF is an inherently inactive endonuclease on its own and was believed to …
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Security, privacy, and trust in crowdsourcing systems
… named content-preserving and semantics-flipping (CPSF) adversarial attacks against natural language processing (NLP) models. We developed a two-stage approach to generate CPSF adversarial examples. Lastly, we proposed to investigate the privacy risks of third party app users in crowdsourcing. We …
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Functional interactions of overexpressed transcripts associated to Broad Copy Number Aberrations (BCNAs) in solid cancers [Interazioni funzionali di trascritti over-espressi associati ad ampie aberrazioni del numero di copie nei tumori solidi]
… Fitness-OverT, tra cui eIF2, eIF3, CSTF e CPSF, in una coorte locale di CRC, nei campioni di adenocarcinoma del colon (COAD) del The Cancer Genome Atlas (TCGA) e nei modelli cellulari. La caratterizzazione molecolare delle linee cellulari di carcinoma colorettale è stata eseguita …
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Factors and mechanisms of archaeal transcription termination and DNA repair
… in Archaea (FttA), a close homolog of the human CPSF subunit CPSF73, is completely conserved throughout Archaea, and appears to act analogously to the bacterial termination factor Rho, terminating transcription after the uncoupling of transcription and translation at the end of protein coding …
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Driver genes associated to Broad Copy Number Aberrations in solid cancers
… protein complexes (eIF2, eIF3, CSTF and CPSF) are candidate targets for silencing transcriptional therapy. At the end, in Glioblastoma multiforme the most recurrent chromosome aberration regards the gain of chromosome 7 alone or in combination with focal amplification of EGFR locus …