Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"CPEB"”.
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Role of Drosophila Orb2 (CPEB) in Synaptic Protein Synthesis
… and persistence of memory. Moreover specific CPEB family members demonstrate biophysical properties that are associated with prion-like proteins. They exist in two distinct physical states: a monomeric and a dominant self-sustaining amyloidogenic aggregated state. This suggested a model in …
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Drosophila CPEB, Orb2, a Putative Biochemical Engram of Long-term Memory
… aggregation of the RNA-binding protein CPEB/Orb2 is one of the candidate mechanisms of memory maintenance. Here, using tools that allow rapid and reversible inactivation of Orb2 protein I find that Orb2 activity is required for encoding and recall of memory. Blocking the Orb2 …
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Identification and characterization of enzymes involved in the biosynthesis of different phycobiliproteins in cyanobacteria
… CpeY, CpeZ, and CpeS was tested on the CpeA and CpeB subunits from <em><em>F. diplosiphon</em></em>. CpeY/CpeZ was found to ligate PEB on CpeA, although CpeY alone had only 60% chromophorylation activity compared to CpeYZ together. Studies with site-directed variants of CpeA (C82S and C139S), …
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Novel Small-RNA Mediated Gene Regulatory Mechanisms for Long-Term Memory
… factor CREB1 and translation factor CPEB respectively. We therefore provide the first evidence that a modulatory neurotransmitter important for learning can regulate the levels of small RNAs and present a novel role for miR-124 and miR-22 in long-term plasticity of synapses in the …
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Regulating transcript fate through RNA elements in the 3' untranslated region
… bodies to polysomes, facilitating translation. CPEB is a family of well studied proteins that takes advantage of the second type of mechanism of post-transcriptional regulation whereby it prevents the binding of translational machinery. It does this primarily by controlling the length of the …