Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"COX pathway"”.
-
Role of the Leukotriene B4 Metabolic Pathway in Human Pancreatic Cancer
… have anticancer effects. Two major metabolic pathways exist for arachidonic acid, namely the cyclooxygenase (COX) pathway and the lipoxygenase (LOX) pathway. Earlier investigations into the role of arachidonic acid metabolism in cancers focused mainly on the COX pathway, because of the …
-
Pharmacokinetics and pharmacodynamics of some NSAIDs in horses: A pharmacological, biochemical and forensic study
… inhibiting prostaglandin (PG) synthesis via the COX pathway. Some of the NSAIDs have adverse side effects including ulceration of the stomach and cardiovascular events which are associated with bleeding. Search is still going on to find a safe NSAID. Two new coxib NSAIDs, namely celecoxib and …
-
Development of Novel, Brain Permeable, mPGES-1 Inhibitors for Inflammatory Conditions
… produced downstream of the cyclooxygenase (COX) cascade. The COX pathway has long been implicated for its role in inflammation, with drugs like aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) non-selectively targeting the upstream COX enzymes to suppress inflammation. …