Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"COAGULATION PROTEINS"”.
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Towards atomistic characterization of blood coagulation proteins by NMR spectroscopy
Proteins involved in the blood coagulation cascade are of vital biomedical importance, and most essential blood-clotting reactions occur preferentially on phospholipid membranes. Understanding the interactions between the proteins and membranes involved in blood clotting is crucial to the continued …
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MOLECULAR MODELING STUDIES OF HEPARIN AND HEPARIN MIMETICS BINDING TO COAGULATION PROTEINS
… heparin with antithrombin is the basis for anticoagulation therapy. Heparin accelerates the antithrombin mediated inhibition of factor Xa and thrombin by a conformational activation mechansism and bridging mechanism, respectively. The sequence specific pentasaccharide DEFGH in full length …
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Studies of structure-function relationships in two human coagulation proteins: factor XII and prothrombin
The epitope(s) of three anti human factor XII monoclonal antibodies were localized by screening a factor XII cDNA expression library in kgt11. One antibody, B7C9, had been shown previously to inhibit the activation of FXII by negatively charged surfaces. The positive recombinant phage contained …
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Assembly of Coagulation Proteases on the Membrane Surface
… the importance of the assembly of the various coagulation proteins on the membrane surface.
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Evaluation of Current Thrombophilia Screening Practices of Internists, Family Physicians, and Obstetricians/Gynecologists: Factor V Leiden Genetic Testing and Referral Patterns
… events by altering the quantity or function of coagulation proteins. Professional organizations, such as the American College of Medical Genetics (ACMG) and the College of American Pathologists (CAP), have published recommendations about the optimal time to test individuals for FVL by mutation …
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The effect of vitamin K On vascular health and physical function in older people with vascular disease
… suggested that vitamin K, a known cofactor for coagulation proteins, may be required for the function of several other key proteins. In particular, Matrix Gla protein may exert beneficial effects on vascular health. I hypothesised that supplementation of the diet with vitamin K would improve …
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Thrombosis in Children
… to ascertain whether autoantibodies against coagulation proteins constitute a risk factor for childhood thrombosis; to study girls receiving estrogen treatment with regard to induced hemostatic changes and efficacy of the therapy; to investigate long-term effects on the hemostatic system in …
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Structural studies of membrane-associated complexes by solid-state NMR
… more than an inert platform supporting membrane proteins and their interactions. It is a complex mixture of lipids, sterols, and proteins, the exact composition of which directly regulates all extracellular interactions and trafficking of materials. The inherent asymmetry of the plasma membrane …
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THE OMEGA-6: OMEGA-3 FATTY ACID RATIO IN SWINE NUTRITION: LONG-TERM EFFECTS ON PERFORMANCE, MILK FATTY ACID PROFILES, OXIDATIVE STATUS, AND PROTEOMES
… altered the plasma levels of several acute phase proteins (APPs) such as HP, SERPINA1, and APCS that might be involved in protective mechanisms against accelerated stresses and, in particular, oxidative stress at later stages of gestation and lactation. Furthermore, significant shifts were found …