Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"CNS injuries"”.
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Der Einfluss der intensivierten Insulintherapie auf Infektionen bei Patienten mit schwerer ZNS-Verletzung
… of intensive care patients suffering from severe CNS injuries requiring prolonged mechanical ventilation, we have investigated the implementation of intensified insulin therapy to inflammatory parameters (CRP, Leukocytes, IL-6, PCT). Further aims of this study, were to see if it would be possible …
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Collagen scaffolds for treatment of penetrating brain injury in a rat model
Recovery from central nervous system (CNS) injuries is hindered by a lack of spontaneous regeneration. In injuries such as stroke and traumatic brain injury, loss of viable tissue can lead to cavitation as necrotic debris is cleared. Using a rat model of penetrating brain injury, this thesis …
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hepatocyte growth factor inhibits glial scar formation and
… impedes growth of regenerating axons following CNS injuries such as spinal cord trauma. Glial scars also produce various species of chondroitin sulfate proteoglycans (CSPGs) that act as a potent inhibitor of axon growth. Thus, inhibition of glial scar formation and/or suppression of CSPGs …
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Retinoic acid signaling after nerve injury
… in the physiological reactions after PNS and CNS injuries. The aim of this thesis was to identify the cellular targets of injury-related RA signals in the peripheral and central nervous system and to investigate the functional significance of RA in this context.I discovered that crucial …
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STUDY OF THE EFFECT OF TUMOUR EDUCATED MACROPHAGES ON NEURAL CELLS
Background: Traumatic injuries to the brain and spinal cord, including spinal cord injury (SCI), represent devastating conditions that lead to permanent loss of function, mainly due to the poor intrinsic regenerative capacity of the central nervous system (CNS). At the lesion site, the hostile …
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Gene therapy for axon regeneration
… adult neurons in the central nervous system (CNS) do not regenerate. Traumatic CNS injuries are a significant clinical problem and have life-changing consequences for patients. There are 130.000 new cases of spinal cord injury (SCI) per year worldwide and currently affects more than 2.5 …