Global ETD Search
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Showing 1 to 2 of 2 for “"CMTR1"”.
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Investigating the Role of the mRNA Capping Enzymes in Mouse Embryonic Stem Cells and Differentiation
… enzymes in pluripotency and differentiation. CMTR1, the first nucleotide O-2 ribose methyltransferase, was found to be upregulated during embryoid body formation, LIF withdrawal and in vitro neural differentiation. The function of CMTR1 in mESCs and differentiation was explored by producing a …
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Investigating the role and regulation of mRNA capping in pluripotency and differentiation
… can be methylated at ribose O2 position by CMTR1 and CMTR2 respectively. The mRNA cap protects transcripts from degradation and recruits cap-binding factors to promote pre-mRNA processing, nuclear export and translation initiation. In mouse embryonic stem cells (mESCs), high levels of RAM …