Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"CMML"”.
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Immunotherapy and immunosuppression in myeloid leukemia
… (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis aimed at contributing to the understanding of the role of natural killer (NK) cells in AML …
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Substratspezifität und Signaltransduktion zellulärer und onkogener Abl-Tyrosinkinasen
… in Formen der sowohl CML als auch der ALL und CMML beschrieben worden. Diese seltener auftretenden Abl-Fusionskinasen umfassen sowohl Bcr-Abl Proteine anderer Größe (p165Bcr-Abl, p190Bcr-Abl und p230Bcr-Abl) als auch die Tel-Abl Fusionskinasen, die anstelle von Teilen des Bcr-Proteins Teile des …
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Causes of Lunda – Luvale conflict and why the problem still exists despite people trying to resolve it: a case of North-western province of Zambia.
… tribe) from Christian Mission in Many Lands (CMML). Study participants were selected using purposive and snowball sampling techniques. The data were collected using semi-structured interviews and were analysed using the Interpretive Phenomenological Analysis (IPA) method, by way of coding and …
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Causes of Lunda – Luvale conflict and why the problem still exists despite people trying to resolve it: a case of North-western province of Zambia.
… tribe) from Christian Mission in Many Lands (CMML). Study participants were selected using purposive and snowball sampling techniques. The data were collected using semi-structured interviews and were analysed using the Interpretive Phenomenological Analysis (IPA) method, by way of coding and …
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Characterization of 5-methylcytosine dioxygenase Tet2 and rescue of mutant Tet2 activity by using turbo co-substrate
… syndrome (MDS), chronic myelomonocytic leukemia (CMML), myeloproliferative neoplasms, and secondary acute myeloid leukemia derived from these conditions. In cancer cells, the normal regulation of 2-OGDDs activity is disrupted, leading to changes in gene expression and epigenetic modifications. The …
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Targeting integrin alpha 5 and focal adhesion kinase to overcome azacitidine resistance in higher risk myelodysplastic syndromes
Myelodysplastic syndromes are typified by bone marrow failure due to profoundly impaired haematopoietic differentiation with higher risk disease commonly progressing to acute myeloid leukaemia. Azacitidine (AZA) and decitabine are the only available therapies for higher risk myelodysplastic …