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Showing 1 to 20 of 34 for “"CHX"”.
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Characterization of NfxB and PA4596, Two Repressors of the mexCD-oprJ Operon Encoding an RND-Type Multidrug Efflux Pump in Pseudomonas aeruginosa
… and several biocides including chlorhexidine (CHX). Expression of mexCD-oprJ is negatively regulated by NfxB, a LacI-type repressor. The promoter region of mexCD-oprJ was identified and included two inverted repeat operator sites, B1 and B2, both of which are required in order for NfxB to bind, …
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Comparison of Antibacterial Activity of Ozonated Olive Oil and Chlorhexidine Gluconate
… olive oil (OzOO) with chlorhexidine gluconate (CHX) against periodontal pathogens, Porphyromonas gingivalis and Aggregatibacter Actinomycetemcomitans. Materials and Methods: The antibacterial activity of two antiseptics, OzOO and CHX, and, two controls, olive oil and normal saline was assessed …
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Untersuchungen zur antibakteriellen Wirkung des Walnussbaumes (Juglans regia) im Vergleich zu Chlorhexidin-digluconat
… untersucht und mit Chlorhexidin-digluconat (CHX;0,2%) verglichen werden. <br>Material und Methodik: In Vorarbeiten wurden Extrakte aus Wurzel und Rinde von Juglans regia hergestellt. Im Agarlochtest auf Diagnostic-Sensitivity-Test-Agar wurden verschieden Zubereitungsformen der Extrakte auf …
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Chemical and physical methods of enhancing the percutaneous absorption of antimicrobial agents
… The hydrochloride salt of chlorhexidine (CHX), a poorly soluble salt, was used throughout this study. The effect of ionisation on in vitro permeation rate across the excised human epidennis was investigated using Franz-type diffusion cells. Saturated solutions of CHX were used as donor and …
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Next generation of electrospun textiles for chemical and biological protection and air filtration
… of blends containing a biocide chlorhexidine (CHX). A small amount of high molecular weight poly(ethylene oxide) was incorporated into the blends to facilitate the electrospinning and a dimensionless Deborah number (De) was introduced to determine the spinnability of the blends. The resultant …
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In–Vitro Evaluation of Effects of Grape Seed Extract and Chlorhexidine on Bond Strength
… different dentin pre-treatments: chlorhexidine (CHX), grape seed extracts (GSE) in acid etchant, and GSE in primer, on bond strength, and to determine the effects of aging with thermal cycling by dentin pre-treatment protocol. Material and Methods: One hundred and twenty bovine mandibular …
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A critical analysis of the 2H NMR data in chlorhexidine-containing model membranes
… (DMPC) and chlorhexidine (CHX) were investigated at several DMPC:CHX molar ratios (1:0,10:1,3:1). Extensive numerical analysis of previously acquired data identi ed the di erences in the temperature-dependence of the order parameters characterizing the rapid molecular …
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Effects of dietary fats on reproductive performance , egg quality, fatty acid composition of tissuse and Yolk and prostaglandin levels of embryonic tissues in Japanese Quail (Coturnix coturnix japonica)
… evaluated. The addition of 5.0% chicken fat (CHX), hydrogenated soybean oil (HSBO), menhaden fish oil (MENH) or soybean oil (SBO) to the maternal and paternal diet altered tissue and yolk composition of the hens and tissue composition of the males to reflect the dietary source. Comparisons …
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Investigating the Link between the Oral Microbiome and Cardiovascular Health in Regards to Nitrate/Nitrite Metabolism.
… study evaluated the effect of chlorhexidine (CHX-M n= 21) and propolis (PROP-M n= 24) mouthwashes on abundance and activity of nitrate-reducing bacteria in healthy individuals. CHX-M increased relative abundance of nitrate-reducing bacteria (P < 0.001), but significantly impaired …
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VIRAL MODULATION OF MHC CLASS II-MEDIATED ANTIGEN PRESENTATION
… with an inhibitor of translation-cycloheximide (CHX). Like VV, CHX negatively regulated Ii protein expression and class II presentation. Ii proteolysis also contributed in part to reduce Ii expression in VV infected and CHX treated APC. Yet only VV infection altered lysosomal protease expression, …
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Polysomes but not translation are required for estradiol-mediated stabilization of Xenopus laevis vitellogenin mRNA
… (MDMP) and cycloheximide (CHX), were determined. MDMP, while inhibiting 89% of translation, caused mRNA's to lose their complement of ribosomes. CHX, while inhibiting 96% of translation, caused mRNA's to retain a full complement of non-translating ribosomes. When …
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THE IMPACT OF CONCUSSION HISTORY ON THE NEAR REFLEX AND PUPILLARY LIGHT REFLEX IN VIRTUAL REALITY
… and patients with a history of concussions (CHX). It was hypothesized that the CHX group’s responses would be reduced, slowed, or delayed, across ocular metrics. Further, we aimed to establish the ability of our novel virtual reality (VR) assessments to elicit stimulus-specific changes in …
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Analyse der in-vivo Funktion der Transkriptionsfaktoren TGA2.1 und TGA2.2 aus Tabak nach Fusion mit einer konstitutiven Aktivierungsdomäne
… des Proteinsynthese-Inhibitors Cycloheximid (CHX), der in-vitro zur schnellen Verstärkung der Bindeaffinität von ASF-1 / SARP an as-1 führt, vermittelten die Fusionsproteine nicht die Aktivierung der Zielgene, was impliziert, dass die alleinige CHX-Behandlung in-vivo nicht die schnelle Bindung …
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Untersuchungen zur Apoptose durch das Kontakthapten NiCl 2 in humanen Nabelschnurendothelzellen
… Z-VADfmk ein; dieser blockierte die NiCl/CHX-vermittelte DNA-Fragmentation und Apoptose vollständig. Im Rahmen physiologischer wie auch pathophysiologischer Vorgänge werden Endothelzellen oxidativem Streß in Form reaktiver Sauerstoffradikale ausgesetzt, die zu einer Heraufregulation von …
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Leveraging Bio-Inspired Molecules for Cancer Theranostics
… methlysulfone-modified variant of the chelator CHX-A′′-DTPA (PODS-CHX-A′′-DTPA) and verified the site-specificity of the conjugation for the reactive lysines within the catalytic domains via chemical assay, MALDI-ToF mass spectrometry, and SDS-PAGE. The chelator-bearing immunoconjugate was …
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The Development of Novel Radioimmunoconjugates for the PET Imaging and Radioimmunotherapy of Cancer
… of chelators to yield [<sup>177</sup>Lu]Lu-CHX-A”-DTPA-PODS-HER2DVD for targeting HER2+ breast cancer. For immunoPET, several chapters of this dissertation are dedicated to discussing the development of a CD133- targeting monoclonal antibody — [<sup>89</sup>Zr]Zr-DFO-aCD133 — majorly …
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Role of plasma membrane ATPase4 in the pathophysiology of pulmonary arterial hypertension
… PAECs and HUVECs with TNF-α and cycloheximide (CHX) significantly reduced PMCA4 mRNA and protein expression. Silencing PMCA4 using siRNA markedly enhanced TNF-α + CHX–induced apoptosis, confirmed by increased TUNEL staining and caspase-3 cleavage. In contrast, BMP9-induced Smad1/5 and …
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Cyclodextrin complexes of antimicrobial agents
… studied were chlorhexidine dihydrochloride (CHX), p-hydroxybenzoic acid esters (methyl, ethyl, proply and butyl) and triclosan. The interactions between the antimicrobials and CyDs were studied in solution and solid phases. Phase solubility studied revealed an enhancement in the aqueous drug …
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Untersuchungen zur Keimbesiedlung von elektrischen Zahnbürsten - ein Vergleich zwischen Schall- und rotierend-oszillierenden Zahnbürsten
… dass eine Dekontamination mit Wasser, eine CHX-Dekontamination und eine Wasserabspülung mit anschließender Lufttrocknung unterschiedlichen Einfluss auf kontaminierte Zahnbürsten haben. Ein statistischer Einfluss des Zahnbürstentyps konnte hingegen nicht gezeigt werden. Auch konnte die …
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An investigation of gene expression, alternative splicing and nonsense-mediated decay in potato in response to Phytophthora infestans infection
… NMD in potato leaves using cycloheximide (CHX) treatment and to look for any effects on NMD of P. infestans infection in potato. Secondly, by developing UPF1-silenced N. benthamiana plants using virus induced gene silencing (VIGS), I explored the role of NMD in R/Avr interactions and …
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