Global ETD Search
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Showing 1 to 3 of 3 for “"CHCHD4"”.
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Investigating the role of mitochondria in the hypoxia response using in vitro and in vivo models
… coiled-coil helix domain-containing protein 4 (CHCHD4) catalyses disulfide bond formation in substrate proteins, mediating their import from the cytoplasm into the mitochondria. CHCHD4 is critical for maintaining intracellular oxygenation and metabolism in human cells, partly by controlling the …
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UNDERSTANDING THE PRO-SURVIVAL ROLE OF AIF: STRUCTURAL AND FUNCTIONAL STUDY OF AIF-CHCHD4 COMPLEX
… è svolto grazie all’interazione di AIF con CHCHD4, una proteina solubile dello spazio inter-membrana dei mitocondri (IMS), che promuove l’ingresso nell’IMS e il folding ossidativo dei substrati appartenenti alle subunità dei complessi respiratori. Dato l'interesse nel chiarire il ruolo …