Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CFU-C"”.
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Targeting integrin alpha 5 and focal adhesion kinase to overcome azacitidine resistance in higher risk myelodysplastic syndromes
… (HSPCs) or bone marrow stromal cells. Using CFU-C assays I show that combining ITGA5 inhibitor or focal adhesion kinase inhibitor with azacitidine could significantly improve the differentiation capacity of AZA resistant HSPCs. To understand the central mechanisms underlying this therapeutic …
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The Role of Gata3 in Blood Stem Cell Emergence
The first definitive haematopoietic stem cells (HSCs) produced during embryonic development are generated from a specialised subset of endothelial cells known as haemogenic endothelium. Recently, it was reported that Gata3 plays a dual role in the development of sympathetic nervous system and …