Global ETD Search

Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies in Cystic Fibrosis: A Retrospective Evaluation of a Nationwide Specialty Pharmacy Database

Mehta, Zumi2021

… fibrosis transmembrane conductance regulator (CFTR) gene. Patients with CF experience excessive mucus build up and infections leading to complications in the pancreas, lungs, and other organs. There has been a paradigm shift in the treatment of CF with the introduction of CFTR modulator …

duquesne Repository record for Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies in Cystic Fibrosis: A Retrospective Evaluation of a Nationwide Specialty Pharmacy Database (opens in a new tab)

Antifungal Immune Responses and Inflammation in the Cystic Fibrosis Airways

Elliot Mahoney (21039332)2026

… (the Cystic Fibrosis Transmembrane Regulator or CFTR), a chloride transporter found in both epithelial and immune cells, results in persistent infections and inflammation in the airways. It has been shown that Aspergillus fumigatus frequently infects the airways of people with CF and contributes …

exeter

Antifungal Immune Responses and Inflammation in the Cystic Fibrosis Airways

Elliot Mahoney (21039332)2026

… (the Cystic Fibrosis Transmembrane Regulator or CFTR), a chloride transporter found in both epithelial and immune cells, results in persistent infections and inflammation in the airways. It has been shown that Aspergillus fumigatus frequently infects the airways of people with CF and contributes …

exeter

Role of the Lipid Environment and Cholesterol Content in the Function of CFTR Modulators

Ravamehr-Lake, Dorna2024

… Fibrosis Transmembrane Conductance Regulator (CFTR). Despite CFTR being a protein located in epithelial cell membranes, it has not been established whether the membrane surrounding CFTR plays a role in the function of the recently-discovered CFTR modulators. In concert with a variety of …

toronto-retro Repository record for Role of the Lipid Environment and Cholesterol Content in the Function of CFTR Modulators (opens in a new tab)

Die Auswirkungen von Elexacaftor–Tezacaftor–Ivacaftor auf neutrophile Granulozyten, Monozyten und Thrombozyten bei Patientinnen und Patienten mit Cystischer Fibrose

Höpfer, Larissa MelinaUniversität Ulm

ulm-diss Repository record for Die Auswirkungen von Elexacaftor–Tezacaftor–Ivacaftor auf neutrophile Granulozyten, Monozyten und Thrombozyten bei Patientinnen und Patienten mit Cystischer Fibrose (opens in a new tab)

Small molecule channels increase anion secretion and host defenses in cystic fibrosis airway epithelia: mechanistic studies and initial clinical translation

Chorghade, Rajeev ShankarUniversity of Illinois at Urbana-Champaign2020

… fibrosis transmembrane conductance regulator (CFTR) anion channel. Loss of CFTR-mediated HCO3- and Cl- secretion to the airway surface liquid (ASL) compromises airway host defenses in people with CF and contributes to the chronic bacterial infection and airway inflammation that characterize CF …

uiuc Repository record for Small molecule channels increase anion secretion and host defenses in cystic fibrosis airway epithelia: mechanistic studies and initial clinical translation (opens in a new tab)