Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"CELL SUSCEPTIBILITY"”.
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Examining the Impact of PUFAs and the Role of Autophagy in Iron-Induced Ferroptotic Cell Death
Ferroptosis, an iron-dependent non-apoptotic cell death involves lipid peroxidation and associates with cardiometabolic disease and cancer. I established a model of iron overload in L6 cells and measured cell viability, toxicity and lipid peroxidation. Importantly, in PUFA pre-treated cells, the …
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Bidirectional Natural Killer Cell and Dendritic Cell Interactions in HIV-1 Pathogenesis
Natural killer (NK) and dendritic cell (DC) interactions are pivotal for the development of immune responses, which lead to bidirectional NK:DC activation. In HIV-1 infection, both NK cell and DC function are impaired, resulting in dysfunctional NK:DC crosstalk. We demonstrate that NK:DC …
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In vivo and in vitro applications of biospectroscopy : potential use as a diagnostic tool which can provide insights into cell cycle dependent proliferation
… applications characterise in vitro and in vivo cells with abnormal proliferation capacities. Proliferation of endometrial tissues in regions other than the uterus lining is known as endometriosis. It affects around 10% of women in the UK and worldwide. This study tests Fourier-Transform Infrared …
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The involvement of the kynurenine pathway in the pathogenesis of multiple sclerosis
… in EAE mice; (4) Oligodendrocytes, the main cell type lost in MS do not express IDO, that could possibly leads to the cell susceptibility towards T-cell cytotoxicity. In conclusion, this study provides strong evidences that the KP is involved in the progression of MS. The above data well …
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Tumor-induced macrophage and T cell dysfunction
Macrophages (MΦ) and T cells mediate helper, effector, and cytotoxic activities. Tumor growth changes the phenotypic and functional characteristics of MΦ and T cells and shifts them toward suppressor phenotypes and functional activities. Tumor growth changed MΦ DNA synthesis when activated through …
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Investigation of Single-Cell and Blood-Brain Barrier Mechanics after Electroporation and in Primary Brain Cancers
Cell-level and tissue-level mechanical properties are key to healthy biological functions, and many diseases and disorder arise or progress due to altered cell and tissue mechanics. Pulse electric field (PEFs), which employ intense external electric fields to cause electroporation, a phenomenon …
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Η ΑΝΤΙΙΚΗ ΔΡΑΣΗ IN VITRO ΠΑΡΑΓΟΜΕΝΩΝ ΙΝΤΕΡΦΕΡΟΝΩΝ ΣΕ ΣΧΕΣΗ ΜΕ ΤΑ ΣΥΣΤΗΜΑΤΑ ΜΕΤΡΗΣΗΣ - ΕΦΑΡΜΟΓΗ ΣΤΗΝ ΑΝΙΧΝΕΥΣΗ IN VIVO ΠΑΡΑΓΟΜΕΝΩΝ ΙΝΤΕΡΦΕΡΟΝΩΝ
… WERE INVOLVED IN IFN-PRODUCTION (PRODUCER CELL AND INDUCER VIRUS) OF THE INDUCED TYPE OF IFN. FROM THE RESULTS WAS INDICATED THAT IFN PRODUCTION, IFN-ASSAY AS WELL IFN DETECTION IN HUMAN SERA DEPENDED ON THE CELL-LINE USED.