Global ETD Search
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Showing 1 to 4 of 4 for “"CEACAM1"”.
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Characterization of CEACAM1 Spatial Distribution, Self-association and Dynamics using High-resolution Microscopy Techniques
… and infection. There is growing evidence that CEACAM1 isoforms regulate the cellular response to CEACAM1-mediated interactions between various cell types. Reinforcing this point, given its potential as a tumour suppressor and immunomodulator, CEACAM1 is being targeted for clinical development. …
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An immunoproteomic approach to identifying cancer-associated autoantibody biomarkers
… Combinatorial ROC analysis indicates that CEACAM1 and GRWD1 as the top autoantigen combination for CRC diagnosis, together producing sensitivity-, and specificity-, and AUC-values of 1.00, 0.77 and 0.94, respectively. Furthermore, other top autoantigens, including COL6A1, THEG and CEACAM7, …
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CEACAM3: ein neuartiger phagozytischer Rezeptor der angeborenen Immunantwort zur Erkennung human-spezifischer Pathogene
… dosisabhängig, wohingegen die Blockade der CEACAM1- bzw. CEACAM6-vermittelten Internalisierung der Gonokokken durch Nystatin keine Auswirkungen zeigt. Auch die Proteintransduktion der dominant-negativen Version von Vav (TAT-Vav-dn) bzw. Rac (TAT-Rac-dn) in primäre Granulozyten interferierte …
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Determinants of Immunity against the Meningococcus
… nasal infection, wherein expression of human CEACAM1 allows N. meningitidis to colonize the murine nose. I reveal that protection against nasal colonization is absolutely reliant on B cells and neutrophils, suggesting that opsonophagocytosis plays a major role in prevention of nasal …