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Showing 1 to 3 of 3 for “"CDS2"”.

  1. An Investigation into the Function of CDS2 in Phosphoinositide Synthesis in Murine Macrophages

    … The aim of this work is to investigate whether CDS2-dependent PI synthesis plays an active role in PIPn signalling and homeostasis under basal and PLC-activated conditions. In CDS2-KO bone marrow derived macrophages (BMDMs), basal PIPn levels are maintained, albeit with a clear steady-state …

    cambridge Repository record for An Investigation into the Function of CDS2 in Phosphoinositide Synthesis in Murine Macrophages (opens in a new tab)

  2. Determining therapeutically actionable genetic interactions in human cancer at scale using multiplexed CRISPR screening

    … high-value paralog pairs (ESCO1/ESCO2, CDS1/CDS2, and DOCK1/DOCK5) were prioritised for further characterisation. Rescue experiments in cell models with inherent loss of one paralog confirmed that this loss creates a dependency on the remaining paralog, reinforcing the SL relationship and …

    cambridge Repository record for Determining therapeutically actionable genetic interactions in human cancer at scale using multiplexed CRISPR screening (opens in a new tab)

  3. Application and analysis of the constant photocurrent method in studies on amorphous silicon and other thin-film semiconductors

    … ‘non-silicon’ materials (i.e. CdTe, GaAs, CdSe & CdS2 ) the applicability of the CPM method to these photoconductive materials is demonstrated in this work.

    abertay Repository record for Application and analysis of the constant photocurrent method in studies on amorphous silicon and other thin-film semiconductors (opens in a new tab)