Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"CD91"”.
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Mechanisms of Molecular Chaperone Surface Binding and Endocytosis: Insights into the Molecular Basis for GRP94 Immune Function
… professional antigen presenting cells (pAPCs). CD91 was the first receptor proposed to facilitate GRP94-mediated immune responses. Using a GRP94 affinity matrix, a CD91 fragment was isolated from the detergent-solubilized membranes of a pAPC cell line. It was then demonstrated that CD91 ligands …
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Anbindung und Aufnahme von Hitzeschockprotein-Antigenkomplexen durch Antigenpräsentierende Zellen
… antigenpräsentierender Zellen postuliert. CD91 wurde als erster Zelloberflächenrezeptor für die Hitzeschockproteine Hsp90, GRP94, Hsp70 und Calreticulin auf Raw264.7 Zellen beschrieben. Unter den in der vorliegenden Arbeit verwendeten Bedingungen exprimierten Raw264.7 Zellen sowohl vor als …
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Polymorphisms in heat shock protein receptors
… in Hitzeschockprotein-Rezeptorgenen wie CD91 und LOX-1 untersucht, welche die immunologischen Funktionen des HSP70 beeinflussen könnten.
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Cancer care services in Greece: A Delphi approach to investigate the views of Healthcare providers and users
Cancer is emerging as a major problem globally and effective cancer care services are needed to lessen its burden on the community. In Greece, oncology health service provision is not located efficiently, resulting in only few patients receiving high quality care. Furthermore, shortages of health …
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Analyzing the functions of human polynucleotide phosphorylase (hPNPaseold-35)
RNA degradation plays a fundamental role in maintaining cellular homeostasis, along with being a part of normal regulatory mechanisms, whether it occurs as a surveillance mechanism eliminating aberrant mRNAs or during RNA processing to generate mature transcripts. 3’-5’ exoribonucleases are …
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Mechanisms underlying genome maintenance and tumour suppression by BRCA2
Inheritance of germline pathogenic mutations in a single BRCA2 allele predisposes carriers to cancers of the breast, ovaries, pancreas, prostate and other tissues. BRCA2 encodes a complex protein of 3418 residues, with multiple distinct regions implicated in different cellular processes including …