Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"CD83"”.
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Regulation des Zelloberflächenmoleküls CD83 durch das Epstein-Barr Virus und Analyse seiner Funktion
… clearly show that the cell surface molecule CD83, belonging to the immunoglobuline superfamily (Zhou et al., 1992), is upregulated after the activation of EBNA2. By using a derivative ER/EB2-5 cell line that constitutively expressed LMP1 I could show that CD83 is still expressed even in the …
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Immunohistochemical Study of Phenotypes of Dendritic Cells in Dental Pulps from Non-Carious and Carious Teeth
… examined with immunohistochemistry, Mature DCs (CD83+) were almost exclusively restricted to pulps from deep caries. Furthermore, CD209+ DCs in deep caries were elevated over other groups and CD209+ cells about doubled the CD83+ cells suggesting that immature DCs had accumulated and were …
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A novel method of generating Dendritic cells in vitro using the KG-1 cell line and its use as a model for testing effects of lactic acid bacteria
… cell surface marker expression. Expression of CD83, CD11c, CD123, CD86, HLA-DR and DC-SIGN was assessed by immunofluorescence and flow cytometry. KG-1 cells stimulated with 10 ng/ml PMA and 100 ng/ml Ionomycin were found to be the ideal model for obtaining Dendritic Like Cells (DLCs) in vitro. …
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Die Rolle von eIF-5A und Kernaktin bei Kernexportprozessen
… Funktion von eIF-5A konnte beim Export der CD83 mRNA in Dendritischen Zellen gefunden werden. Es konnte gezeigt werden, daß der Export der CD83 mRNA durch das RNA-bindende Protein HuR und durch den generellen Exportrezeptor CRM1 vermittelt wird. Durch den HuR Lignaden APRIL, der ein …
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Investigating the Immunological Effect of Schizophrenia-Related Antigens and Anti-psychotic Medication.
… could induce an increase in the proportion of CD83 positive cells and apoptotic cells; antipsychotic treatment generated a dose-dependent reduction in both cell number and viability. Taken together, this PhD work identified novel autoantibodies that might play a role in underlying …
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Investigations into the Biological Roles of the E3 ligase Ariadne 2/TRIAD1
… of maturation markers CD80/B7.1, CD86/B7.2, CD83, CD40 and MHCII and are capable of activating T cells in the RIP-GP model of induced diabetes. This may be linked to modulation of the NFκB and ERK pathways, in particular increase in nuclear p65/RelA and phospho-p65/RelA leading to an increase …
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Characterization of Innate Immune Mechanisms Against RVFV and a Potential Target for Antivirals
… maturation marker presentation of CD40, CD86 and CD83 and were also able to induce higher levels of proinflammatory molecules while rMP-12 and rMP12-delNSm/78 viruses (expressing functional NSs protein but lacking 78 kDa protein and NSm) did not. We found that NSm does not play a major role in DC …
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Modulation of the immune response by current and novel treatments for hepatitis C virus
… of phenotypic markers (CD40, HLA-DR, CD83 and CD86) and enhanced pro-inflammatory cytokine production (IL-6, IL-8 and TNF?). It was also shown to stimulate proliferation of allogeneic CD4+ T cells suggesting that the protein is able to enhance the accessory/antigen presentation by DCs. …
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Untersuchung des CRM1-abhängigen RNA-Exports mittels Repräsentativer Differenz-Analyse
… Transkripte wie z.B. die TNFalpha- oder die CD83-mRNA identifiziert werden, die eine veränderte Kern/Cytoplasma-Verteilung nach LMB-Behandlung zeigten. Mit Northernblot- und RT-PCR-Analysen konnte zusätzlich bewiesen werden, daß die Transkription der meisten untersuchten mRNAs durch …
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Development of an Autologous Human Dendritic Cell Vaccine against Mycobacterium tuberculosis in Patients with Extensively Drug-Resistant Tuberculosis
… significantly higher upregulation of CD80, CD83, CD86, and CCR7 (p< 0.001 for all comparisons), and higher secreted levels of IL12p70 (0.67 versus 0.01 ng/mL per 106 cells; p< 0.001). A similar pattern was seen in the containment experiments: mycobacterial stasis within the XDR-TB group was …
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Simulation study of frequency estimators
We develop a frequency estimator employing Kalman filter algorithm for rapid online frequency estimation in both additive white Gaussian noise channel and static fading channel. A new measurement model is proposed, which can describe the phase noise more accurately, thus improves the performance by …