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Showing 1 to 4 of 4 for “"CD82"”.
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Isolation und molekulare Charakterisierung des Apoptose-induzierenden Metastasensuppressors C33/CD82
… Aus diesen wurde das Metastasensuppressorgen C33/CD82 für weitere Untersuchungen ausgewählt, da seine Expression in zahlreichen stark metastasierenden Tumoren herabreguliert ist und es bislang nicht als proapoptotisch beschrieben wurde, obwohl es eines der bislang bestcharakterisiertesten …
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The Role of the YXXΦ Motif in CD82 Trafficking and Function
<p>CD82, a tetraspanin, is a tumor metastasis suppressor. Tetraspanins are membrane spanning proteins that play critical roles in diverse biological and pathological processes, e.g., the regulation of cancer metastasis. CD82 is ubiquitously expressed in various types of tissues, but its expression …
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Tetraspanin KAI1/CD82 inhibits cell migration-related cellular events via reorganizing actin network
<p>To determine how tetraspanin KAI1/CD82, a tumor metastasis suppressor, inhibits cell migration, we assessed which motility-related cellular events are altered by KAI1/CD82 and how KAI1/CD82 regulates these events. We found that KAI1/CD82-overexpressing cancer cells exhibit various morphologies …