Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CD8+ T-cell Exclusion"”.
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Assessing the temporal role of miR-200 loss in murine models of NSCLC
… deaths in the United States, with non-small cell lung cancer (NSCLC) making up a majority of new diagnoses. Metastasis is the big killer in NSCLC and is driven by epithelial-mesenchymal transition (EMT) and immune evasion. The microRNA 200 family is a master regulator of EMT and is implicated …
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Insights into the role of hepatic stromal cells and the immune checkpoint protein PD-L1 in liver metastases of pancreatic cancer
… disseminated pancreatic ductal epithelial cells (PDEC) remains unclear. While hepatic stellate cells (HSC) dominate physiological liver contexts, hepatic myofibroblasts (HMF) prevail under inflammation. Despite success in other cancers, PD-1/PD-L1 therapies show limited efficacy in PDAC, …