Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"CD43"”.
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Functional analysis of murine CD43 shedding : a role for the CD43 cytoplasmic tail in nuclear signalling
CD43, a representative of the leukocyte mucin family proteins, is a transmembrane protein highly expressed on most lymphohemopoietic cells and is believed to play a role in the regulation of leukocyte activation and/or migration. CD43 was shown to be proteolytically shed from human cells and high …
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The role of CD43 in the growth and pathogenesis of Mycobacterium tuberculosis within the mammalian host
… We characterized the role of the glycoprotein CD43 in the pathogenesis of M. tuberculosis. Using gene-deleted mice (CD43-/-), we assessed association of the bacterium with macrophages and found that CD43 was required for optimal binding of M. tuberculosis strain Erdman by splenic, peritoneal, …
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Natural and Exogenous Genome Editing In Wiskott-Aldrich Syndrome Patient Cells
… as control. GFP expression was pronounced in all CD43+ hematopoietic lineages including myeloid, monocytic, lymphoid, erythroid and megakaryocytic lineages. Hematopoietic precursors were further cultured on OP9-DL1 to generate NK cells. NK cells were readily obtained from cWAS and WA01/WA09 …
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CATALYTIC-INDEPENDENT FUNCTIONS OF KDM6A IN B CELL MATURATION AND IMMUNE REGULATION
… an atypical population of Cd21loCd23loCd11b+Cd43+ B cells in the spleen, closely resembling aged B cells. Immunoblotting analyses ruled out major changes in global H3K27me3 levels in Kdm6a mutant B cells. Chromatin accessibility studies indicated that the genome-wide map of accessible regions …
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A chemical biology study of human embryonic stem cell pluripotency and differentiation
… of a DiI-Ac-LDL+VE-cadherin+CD31+CD34+KDR+CD43- endothelial progenitor population, and identified a previously unknown VEGFR3+ progenitor population which may be responsible for human embryonic lymphatic development. This system provides a rare opportunity to visualize a truly spontaneous …
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Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia
… B-cell surface antigens except B220 and CD43.</p> <p>The <em>Pax5<sup>+/+</sup></em> and <em>Pax5<sup>+/-</sup></em> leukemias were monoclonal while the <em>Arf<sup>+/-</sup></em> and the compound heterozygous (<em>Pax5</em><sup>+/-</sup> <em>Arf</em><sup>+/-</sup>) leukemias were …
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Regulators of CD8+ T-cell mediated vaccine immunity against pulmonary fungal infections
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-08-01
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The Role of Gata3 in Blood Stem Cell Emergence
The first definitive haematopoietic stem cells (HSCs) produced during embryonic development are generated from a specialised subset of endothelial cells known as haemogenic endothelium. Recently, it was reported that Gata3 plays a dual role in the development of sympathetic nervous system and …