Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"CD41"”.
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Effects of HOXB4 downstream targets on the haemopoietic differentiation of pluripotent stem cells
… conditions generated 8- 10 fold more CD144+CD41+ and c-Kit+CD41+ haemopoietic progenitor cells (HPCs) compared to serum conditions from both ESCs and EpiSCs, with ESCs giving the most significant increase. We then validated the panel of HOXB4 target genes by QRT-PCR and selected those …
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Differenzierungsabhängige Modulation der Zytokin- und Chemokinexpression bei humanen myeloischen Zell-Linien
… CD14, CD15, CD18, CD19, CD33, CD34, CD38, CD40, CD41, CD42b, CD45, CD45RA, CD45RO, CD61, CD69, CD71, CD95, CD154, Glykophorin A, HLA-DR), der Zytochemie (Myeloperoxidase, Lysozym, unspezifische Esterase) und der Zellmorphologie untersucht. Es zeigte sich, daß sich das Zytokin- und Chemokinprofil …
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Die fibrinogenabhängige Interaktion von polymorphkernigen Granulozyten und Thrombozyten und ihre Bedeutung im reperfundierten Herzen
… Hilfe monoklonaler Antikörper gegen CD11b und CD41 im FACS gemessen. Die Versuche erfolgten vor und nach der Koronarpassage durch ein postischämisches isoliertes Meerschweinchenherz, sowie mit und ohne c7E3Fab/LPM19c Inkubation. PMN/Thrombozytenkoaggregate wurden im koronaren Effluat mittels …
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Comparison of platelet counting technologies in equine platelet concentrates
… antibody against integrin alpha αIIbβ₃ (anti-CD41/CD61) and a fluorescent secondary antibody. Measured platelet concentrations were compared using Passing and Bablok regression analyses and mixed model ANOVA. The Magellan PRP system yielded mean (± SD) platelet and WBC counts of 893,090 ± …
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Distinct functional effects of NMDA receptors in normal and leukaemic megakaryocytes
… primary culture systems: bonemarrow explants, CD41-enriched and lineage-depleted cultures. Finally, NMDAR inhibition was associated with distinct cytoplasmic vacuolation in both leukaemic and normal cells. This was shown not to be due to apoptosis; the nature and significance of this phenomenon …
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Identificação e quantificação de vesículas extracelulares plasmáticas em pacientes com lúpus eritematoso sistêmico atendidos no Hospital Universitário Antônio Pedro em associação com a atividade da doença e imunossupressão
… gerais de EVs), CD45 (marcador de leucócitos) ou CD41 (marcador de plaquetas). Dados clínicos, laboratoriais e demográficos foram obtidos a partir dos prontuários e confirmados pela equipe médica. RESULTADOS: Foram incluídos 43 pacientes, sendo a maioria do sexo feminino (n=40, 93%), não …
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Modelling Embryonic Haematopoiesis Using In Vitro State-of-art Gastruloid Culture
… markers in flow cytometry assays (Flk-1, c-Kit, CD41 and CD45). Concomitant use of cytokines VEGF and FGF2 can facilitate the emergence of cells with the property of haemogenic endothelial cells, pro-HSCs and type 1 pre-HSCs from 96 to 144 hr. Applying Shh, Flt-3l, TPO, and SCF accordingly can …
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The Role of Gata3 in Blood Stem Cell Emergence
The first definitive haematopoietic stem cells (HSCs) produced during embryonic development are generated from a specialised subset of endothelial cells known as haemogenic endothelium. Recently, it was reported that Gata3 plays a dual role in the development of sympathetic nervous system and …
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Neurosteroids: endogenous analgesics?
Peripheral sensitisation and central sensitisation are implicated in the development of neuropathic pain with neuroplasticity occurring at multiple levels of the pain pathway. Hypersensitivity of the spinothalamic tract has been described in neuropathic animal models of diabetes. Spinal dorsal horn …