Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 31 for “"CD4 cell count"”.
-
Stochastic modelling of HIV/AIDS epidemiology with TB co-infection drug reaction in South Africa
… par titions the HIV infection period into five CD4-cell count intervals followed by the end points, that is, death and withdrawal from study. The analysis is based on transition probabilities, transition rates (hazards), mean sojourn times, and time to absorption. The effects of the covariates, …
-
Oral lesions in hiv/aids patients before and after haart treatment
… of viral replications followed by an increase in CD4 lymphocytes, a partial recovery of T-cell specific immune responses and decrease susceptibility to opportunistic pathogens. Aim: The aim of the present study was to determine the prevalence of oral lesions in patients before and after undergoing …
-
Aspects of Tuberculosis and HIV Coinfection in Patients at Ethiopian Health Centers
… of TB on the immune system, both on peripheral CD4 cells and neopterin as a marker of immune activation. In paper III, we found that 25% of HIV negative patients with TB had low CD4 cell count (below 500 cells/mm3). These levels increased until end of TB treatment but not to levels found in …
-
The feasibility and effectiveness of universal antiretroviral therapy provision in adults: The Treat-All approach in the public-sector in rural Swaziland
… clinical (e.g. higher WHO clinical stage, lower CD4 cell count), and programme factors (e.g. toxic drug regimens). The second paper investigates the feasibility of ART initiation under Treat-All compared with SOC. ART initiation was higher and quicker under Treat-All, mainly because more patients …
-
Social and Clinical attributes of patients who restart Antiretroviral Therapy at 5 ART Centers in Central and Copperbelt Provinces of Zambia
… between the socio-demographic characteristic and CD4 cell count over time, quantile regression models were used. Results: A total of 535 patients adults restarted ART of which 303(56.6%) were female. The proportion of patients that restarted was found to be 21.1%. Most of the patients who …
-
Social and Clinical attributes of patients who restart Antiretroviral Therapy at 5 ART Centers in Central and Copperbelt Provinces of Zambia
… between the socio-demographic characteristic and CD4 cell count over time, quantile regression models were used. Results: A total of 535 patients adults restarted ART of which 303(56.6%) were female. The proportion of patients that restarted was found to be 21.1%. Most of the patients who …
-
Adherence to antiretroviral treatment (ART) among HIV-infected pregnant women starting treatment immediately vs delayed: a cohort study
… 2014. Before July 2013, eligibility was based on CD4 cell count ≤350 cells/μL ("Option A"), with a 1-2 week delay from the first ANC visit to ART initiation; thereafter all women were eligible regardless of CD4 cell count ("Option B+") and typically offered ART on the same day as first ANC visit. …
-
Efavirenz pharmacogenetics and metabolic toxicity in black South Africans
… genotyped. Median baseline age was 32 years, CD4 count was 292 cells/mm3 and log10 viral load was 4.42 copies/ml. Univariate analyses showed significant associations between CYP2B6 slow metaboliser genotype and total cholesterol (β = 13.78, p = 0.003), LDL cholesterol (β = 15.89, p = 0.008) …
-
Factors associated with mortality among Tuberculosis patients on treatment in Limpopo Province, South Africa, from 2013 to 2018
… of 0.032. There was a clear association between CD4 cell count range among TB patients and mortality. The mortality among TB patient with a CD4 count less than 50 was 20.4%, which V was the highest and the difference was statistically significant with a p value less than 0.0001. Mortality among …
-
Effects of diabetes mellitus on virologic and immunologic outcomes of patients on first line antiretroviral therapy in a military population in South Africa
… Viral Load (VL) defines virologic status and CD4 cell count defines immunological status in both groups over a 12-month period in South African military setting, comprising six different antiretroviral (ARV) roll out sites. The relationship between VL and CD4 cell counts in terms of …
-
Effect of Human Immunodeficiency Virus Infection on Human Papillomavirus Clearance among Women in Senegal, West Africa
… Incident HPV infections in women with CD4 cell counts ≤500 were 37% less likely to be cleared than those in women with CD4 cell counts >500 (adjusted HR=0.63, 95% CI: 0.41-0.97), but the association was not significant for prevalent HPV infections (adjusted HR=0.87, 95% CI: 0.46-1.63). …
-
Risk of Cardiovascular Disease Inhibitors Among HIV seropositive Adults on Protease Inhibitors Containing Antiretroviral Therapy at Adult Infectious Disease Centre at the University Teaching Hospital
… ART group. Associated factors include; age, CD4 cell count, type of ART, years since HIV diagnosis and BMI. Kaplan-Meier survival estimates for CVD showed a statistical difference (log-rank; p=0.003) in the two groups (PI and non-PI), were survival was more in the non-PI group, hence a higher …
-
Public health nutrition intervention to delay the progression of HIV to AIDS among people living with HIV (PLWHIV) in Abuja, Nigeria
… and overall socioeconomic development in countries that have been greatly affected by the disease. The engagement of HIV/AIDS with under nutrition form a symbiotic relationship and one increases the prevalence and severity of the other. Aim: The main goal of the study was to evaluate the …
-
Evaluating individuals with extreme phenotypes of HIV-1 contributes towards better healthcare management of all HIV-1 positive individuals
… for at least 6 months, RPs – at least one CD4 cell count < 100 cells/mm3 within one year of HIV-1 seroconversion. Evidence shows that less than 1% of individuals are EC and the majority should start treatment to maximise quality and length of life. We supported the ‘when to start’ evidence …
-
Antiretroviral therapy use during pregnancy and adverse birth outcomes in South African women
… adjusting for maternal age, parity, height, CD4 cell count and viral load at 1st visit. Conclusions Levels of adverse birth outcomes, in particular PTD, remain high among HIV-infected women, however our findings from a routine care cohort demonstrate that the timing of initiation of widely …
-
An evidence-based algorithm for the rapid diagnosis of tuberculosis in HIV positive patients presenting to emergency centres
… (c-statistic 0.82; 95%CI 0.78–0.86). Adding CD4 cell count did not improve the performance of the model. Classification And Regression Tree (CART) analysis positioned urinary lipoarabinomannan as the optimal screening test after WHO symptoms (75% true positive rate, representing 17% of …
-
Human immunodeficiency virus type 1 diversity in patients initiating treatment in Northern South Africa
… by suppressed viral loads and increase in CD4+ cell counts to healthy human ranges. This in turn is expected to reduce HIV transmission thereby, leading to a decreased spread of the virus and eventual elimination of the virus from the human population. Findings from these trials resulted in …
-
Impact of introducing an HIV-PCR test at birth to attendance at follow-up early infant diagnosis (EID) services for HIV-exposed infants in Cape Town
… analyses adjusting for maternal age, nadir CD4 cell count, ART use during pregnancy, gestation, infant sex, birthweight and infant feeding modality (Adjusted odds ratio, 0.60 95% confidence interval, 0.40-0.88). Conclusions: Neonates undergoing HIV testing at birth may be less likely to …
-
A description of HIV-exposed uninfected infants in the IeDEA Southern Africa Cohort and an examination of growth outcomes
… and 10.6% formula feeding. Mothers with a CD4 <200 cells/μl delivered infants with a lower birth WAZ (adjusted ß -0.253 [95% CI -0.043; -0.072], p = 0.006) compared to mothers with a CD4 ≥500 cells/≧l. Similarly, iv mothers who did not receive antiretroviral (ARVs) drugs delivered infants …
-
Adherence to highly active antiretroviral therapy among patients in the Keetmanshoop antiretroviral therapy programme, Namibia
… ART clinic. 2. To assess the changes in CD4 count and body weight of clients on HAART over a 12 month period.3. To assess factors associated with adherence to HAART.4. To analyse associations between CD4 count and adherence. 5. To analyse associations between changes in body weight and …
Page 1 of 2