Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"CD4+-CTL"”.
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Characterization of an IL-12-driven Anticancer Response, and the CD4+ CTL Population Incited, in a Murine Model of Leukaemia
… activation of a cluster of differentiation 4 (CD4)+ effector population that affects leukaemia cell clearance both in vitro and in vivo. This work, and the future studies proposed, will expand our understanding of the potential of IL-12 immunotherapy and enhance our ability to manipulate …
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Zytotoxische-T-Lymphozyten (CTL)-vermittelte Zytolyse bei der HIV-Infektion
… HIV-spezifische zytotoxische T-Lymphozyten (CTL) bewirkt wird, untersucht. Grundsätzlich erscheinen in der Abwehr viraler Infekte sowohl CD4+ wie CD8+ CTL. In chronisch HIV-Infizierten sind in der Regel lediglich CD8+ CTL zu finden. HIV-spezifische CD4+ CTL können aber zum Beispiel in …
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ROLE OF IL-10 PRODUCING EOMES+ TR1-LIKE CELLS IN MELANOMA
… transfer experiments with IL-10-deficient FOXP3-CD4+ T cells confirmed the critical role 7 of Tr1-derived IL-10 in promoting tumor progression and impairing anti-tumor immunity. Furthermore, therapeutic treatment with anti-PD-L1 antibodies reduced T cell IL-10 production and inhibited tumor …