NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 1090 for “"CD4"”.

  1. Lipopolüsahhariidi ja interleukiin-2 toime hiire CD4+CD25+ ja CD4+CD25- rakkudele

    Lilleoja, Rutt2007

    tartu

  2. Lentiviral Nef-mediated CD4 and CD28 downmodulation

    Heilmann, JessicaUniversität Ulm

    ulm-diss Repository record

  3. Targeting the CD4 Binding Site of HIV

    von Boehmer, Lotta

    … locus in mice. 3BNC60 is a bNAb that targets the CD4 binding site (CD4bs) of HIV-1 and belongs to the IgHV1-2 class of broadly neutralizing CD4bs antibodies. In the first part of my thesis I will describe the evolution of the HIV-1 antibody response in GLVH and MuVH mice upon immunization. We …

    rockefeller Repository record

  4. Intestinal CD4+T Cell Responses to Food

    Lockhart, Ainsley

    … critical homeostasis. Oral tolerance requires CD4<sup>+</sup> T cells including specifically regulatory T cells (Tregs), however the role of intestinal CD4<sup>+</sup> T cells and the T cell repertoire in a physiological response to food protein remains largely unexplored. To characterize …

    rockefeller Repository record

  5. Developmental Regulation of the Murine CD4 Gene

    Hansen, Rhonda Kay

    <p>CD4 is a membrane bound glycoprotein that plays an important role in T cell development and activation. An extensive analysis of the CD4 locus identified potential transcriptional control elements located 5' of the promoter and within the first intron. Since the molecular mechanism for the …

    loma-linda Repository record

  6. How CD4+ T Cells Recognize Allostimulatory Peptide-MHC

    Ni, Peggy Pei-wen2016

    … whether tolerance is achieved or not, are CD4+ T cells that can recognize peptides presented on allogeneic (non-self) Major Histocompatibility Complex (MHC) molecules in addition to their conventional ligands, peptides presented on self MHC. It is an enigma as to how these alloreactive T …

    wustl Repository record

  7. Telmisartan inhibiert die Chemokininduziete Migration CD4-positiver Lymphozyten

    Raps, Katrin VerenaUniversität Ulm

    ulm-diss Repository record

  8. On Modeling HIV Infection Of Cd4+ T Cells

    Comerford, Amy

    … an early model for the interaction of HIV with CD4+ T cells in vivo and define possible parameters and effects of said parameters on the model. We then examine a newer, more simplified model for the interaction of HIV with CD4+ T cells that also considers four populations: uninfected T cells, …

    ucf

  9. Biological effects of trogocytosis on CD4+ T lymphocytes

    Osborne, Douglas Grant

    <p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …

    montana-tech Repository record

  10. Biological effects of trogocytosis on CD4+ T lymphocytes

    Osborne, Douglas Grant

    <p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …

    montana Repository record

  11. Immunomodulatory effect of pneumolysin upon CD4 T cells

    Meiklejohn, Gordon R.University of Glasgow2004

    … the heart of the adaptive immune response; the CD4 T cell. I generated purified pneumolysin and a purified pneumolysin mutant called F433 to allow me to examine this potential effect. I found that pneumolysin inhibits in vitro antigen specific murine CD4 T cell proliferation and cytokine …

    glasgow Repository record

  12. The CD4⁺ T Cell Response to Human Cytomegalovirus

    Lim, Yiling EleanorUniversity of Cambridge2021

    … of peripheral blood mononuclear cells (PBMCs), CD4+ cells, CD8+ T cells, and natural killer (NK) cells to HCMV infection of autologous fibroblasts in healthy HCMV-seropositive and HCMV-seronegative adults, and showed that there were inherent differences in the ability to control HCMV …

    cambridge Repository record

  13. Dynamics of Naive and Memory CD4 T-cells in Chronically Infected HIV Patients Post-Injection of Down-Modulated CCR5 Memory CD4-Cells

    Raad, Angie2016

    … individuals worldwide. This retrovirus targets CD4 T-cell populations, the main driver of the immune system by using the chemokine co-receptor 5 (CCR5). Despite the success of the highly active antiretroviral therapy in reconstituting the immune system, HIV infected individuals still suffer from …

    york Repository record

  14. CD4+ T cells in the pathogenesis of visceral leishmaniasis

    Medina, Audrie AThe University of Texas Medical Branch at Galveston2019

    … infection is dependent on Th1 (IFNγ producing) CD4+ T cells, which activate macrophages to produce nitric oxide and kill the intracellular parasites. Despite there being an expansion of CD4+ T cells and an increase in pro-inflammatory molecules in the spleen, humans with active visceral …

    utmb Repository record

  15. Effector CD4⁺ T lymphocytes in the prodrome of polyarthritis

    Brasted, Melissa2002

    … polyarthritis, the activation and phenotype of CD4⁺ T cells during the prodrome of adjuvant-induced arthritis (AA) has been investigated in rats. Research in the Arthritis Research Laboratory has demonstrated previously that activated CD4⁺ T cells in the thoracic duct (TD) lymph of rats during …

    adelaide Repository record

  16. Characterising the gene regulatory landscape of CD4+ T cells

    Glinos, Dafni AnnaUniversity of Cambridge2019

    … overlap with active regulatory elements in CD4+ T cells, and particularly in regulatory T cells (Tregs). CD4+ T cells are the orchestrators of the adaptive immune response and their dysfunction has been associated with immune-mediated disorders through uncontrolled activation and resistance …

    cambridge Repository record

  17. Decoding CD4+ T cell activation by multi-modal phenotyping

    Matte, JulieUniversity of Cambridge2024

    The activation of CD4+ T cells is strongly implicated in the biology of immune-mediated diseases, yet the molecular and functional mechanisms governing this process remain incompletely understood. With the explosion of profiling and functional genomic methods in the last decade, it is now feasible …

    cambridge Repository record

  18. Synthesis and CD4 down-modulation potencies of CADA head analogs

    Ali, Rameez2015

    … expression of the transmembrane protein CD4 by blocking its co-translational translocation across the ER membrane. By this mechanism, CADA compounds prevent entry of HIV into host cells. Previous studies of solid-state conformations and structure-activity relationships suggest that CADA …

    unr Repository record

  19. Role of CD4+CD25+ Regulatory T Lymphocytes in Experimental Toxoplasmosis

    Varikuti, Sanjay

    … the present study was to investigate the role of CD4+CD25+ T regulatory lymphocytes in mice infected with <i>Toxoplasma gondii</i>. T regulatory (Treg) cells have been shown to play an important role in our immune system in controlling the activity of other T lymphocytes. These cells are …

    wku-diss Repository record

  20. Cd4 T Cell Activation And Ox40 Agonist Immunotherapy In Tuberculosis

    Gress, Abigail2023

    … with Mtb to distinguish recently activated CD4 T cells from others in the lungs. Recently activated Nur77-GFPHI cells more often expressed protective markers and were enriched for expanded TCR clonotypes. Nur77-GFPHI cells differentially expressed co-stimulatory genes including Tnfrsf4/OX40 …

    umn Repository record

Page 1 of 55