Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 63 for “"CD31"”.
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Lung Progenitor Cell Transplantation for Pulmonary Fibrosis and Ex Vivo Expansion of Patch-Forming EpCAM⁺CD31⁺ Cells
… potential resides within the small CD45-CD326+CD31+ subpopulation. However, these studies also indicated that in this mouse model successful transplantation requires vacating the lung niches in recipient mice of endogenous lung progenitors which otherwise compete with donor derived progenitors …
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Differentiation plasticity of stromal vascular fraction cells towards adipose tissue and endothelial structures
… or excised adi-pose tissue and separated into CD31+ and CD31- populations by magnet-assisted cell sorting. Differentiation to fat tissue was induced in both CD31 fractions. Differentiation was assayed enzymatically and by cell counting. Maturation to endothelium was performed with vascular …
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Skeletal muscle pericyte response to acute and chronic electrical stimulation
… flow cytometry in all samples. NG2+CD45-CD31- and CD146+CD45-CD31- pericytes were isolated following the acute study and gene expression was evaluated using high throughput qPCR. RESULTS: Acute electrical stimulation resulted in a non-significant trend for an increase in total pericyte …
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Molecular events governing hematopoietic stem cell recruitment in Vivo in murine liver following Ischemia-reperfusion injury
… on HSCs or VCAM-1 in vivo. Blockade of HSC CD18, CD31 or CD44 did not alter adhesion. HSC adhesion in sham treated CD31-/- animals was raised compared to wild-type animals and IR injury did not further raise this adhesion. Studies in vitro demonstrated that HSC treatment with inflammatory …
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Hypoxia regulated pathways in urological malignancies
… was made with tumour angiogenesis (CD31), tumour stage, Fuhrman grade,<br/>maximum tumour diameter and patient survival. Further work in this thesis analysed a series of<br/>paired VHL (functional and non-functional) ccRCC cell lines, assessing for hypoxic differential<br/>MicroRNA …
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IN-VITRO VASCULARIZED TISSUE EQUIVALENTS FROM HUMAN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL AND VASCULAR SMOOTH MUSCLE CELLS
… we demonstrate the differentiation of CD34+CD31+ cells into homogeneous populations of arterial and venous ECs under serum-free conditions. Similarly, the CD34-CD31- are differentiated to vSMCs under smooth muscle differentiation conditions and characterized. A prerequisite to realize the …
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Estudio de las micropartículas circulantes en la esclerosis múltiple
… CD51+, incrementadas de manera crónica y las CD31+/CD42-en los brotes. Además, se ha comprobado la reducción de los niveles de micropartículas endoteliales en sangre en repuesta al interferón ß. En un estudio in vitro la presencia de micropartículas endoteliales facilita el paso de los …
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Vasculogenic mimicry in bladder cancer and its association with cancer stem cells and human chorionic gonadotropin-beta
… staining technique with endothelial cell marker CD31 and periodic acid Schiff’s (PAS) and the statistical analysis showed that there was a significant association between stages (P=0.038) of bladder cancer and the presence of VM. However, there was no significant association between grades of …
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PALMITATE INDUCED ENDOTHELIAL DYSFUNCTION: THE ROLE OF CALPAIN, AMPK AND ENOS
… successfully established a stable protocol that CD31 antibody conjugated microbeads were used to isolate primary microvascular endothelial cells from fresh mice lung tissue. After second sorting, CD31+ cells reach 83.3% by FACS analysis. Previous literatures showed that FFAs activate recruitment …
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Development of a stem cell-based therapy for the recovery of skeletal muscle mass following immobilization
… 14 days of remobilization post-disuse. NG2+CD31-CD45- and CD146+CD31-CD45- pericytes were collected using fluorescence-activated cell sorting (FACS) following the remobilization period, and gene expression was analyzed as a readout of functionality. Finally, both pericyte populations were …
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Therapeutic Aerobic Exercise in a Mouse Model of Breast Cancer: Effects on Tumor Progression, Angiogenesis, and Response to Chemotherapy
… significant increases in microvessel density (CD31) and vessel maturity (colocalization of CD31 with NG2 and desmin). Hypoxia (EF5) was significantly reduced in the exercising animals, and MRI showed that tumors were more uniformly perfused in the running groups. Furthermore, exercise …
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Age-dependent changes in the mouse lymph node and implications for immune responses
… I conducted single-cell RNA sequencing on gp38+ CD31- lymph node stromal cells as well as lymphocytes, from adult and aged mice after immunisation. Employing a hypothesis-free approach, I examined age-dependent changes in cell population and identified some differentially expressed genes in adult …
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Yap1 Expression Predicts Sensitivity to Dual Akt/P70S6K Inhibition In Ovarian and Uterine Malignancies
… reduced proliferation (Ki67) and angiogenesis (CD31) indices and increased cell death (cleaved caspase-3) markers. Synergy between MSC2363318A and paclitaxel was observed <em>in vitro </em>in protected (IC50 ≥ 5 µM) cell lines. RPPA identified YAP1 as a candidate marker to predict cell lines …
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Duchenne muscular dystrophy and extraocular muscle: a potential sparing mechanism with therapeutic implications.
… stem or differentiation markers (Sca-1, CD45, CD31, pax-7, m-cadherin) exists in the EOM. We refer to this population as EOMCD34 cells. The EOMCD34 cells are present in developing muscle, but only maintained in adult EOM, surviving in very aged animals. The EOMCD34 cells are also present in EOM …
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Phenotypic and functional analysis of organ specific endothelial cells
… to pro-inflammatory insult (Endoglin, CD34, CD31). Some artefacts of immortalisation were also apparent (VCAM-1 expression in mUCEC-1 and LYVE-1 in s.END). Functional assays indicated small differences in cell types and further microarray analysis elucidated further candidates, including …
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Granulocyte Colony-Stimulating Factor Minimizes Negative Remodeling of Decellularized Small Diameter Vascular Graft Conduits but Not Medial Degeneration
… enhanced staining for von Willebrand factor and CD31, along with transmission electron microscopy findings of superior cellular and ultrastructural preservation, suggested that the remodeling and endothelialization in the +GCSF conduits were superior to those in the Decell conduits. CONCLUSIONS: …
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Evaluation der Wirkung von Bisphosphonaten auf die Tumorangiogenese und ihre Bedeutung in der adjuvanten Tumortherapie
… 3D-Sphäroid-Modell, Kinasescreening, CD31-Antikörperfärbung, VEGF-Serumkonzentration). Dabei unterscheiden sich die verantwortlichen antiangiogenen Mechanismen der beiden untersuchten Bisphosphonate. Die Hemmung der Farnesyldiphosphatsynthase des Mevalonatweges und der dadurch …
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Einfluß von PTK787/ZK222 584, einem spezifischen Rezeptor-Tyrosinkinase-Inhibitor, auf Anatomie, Dichte, Permeabilität und Blutfluß in Tumorgefäßen im murinen Nierenzellkarzinom
… der A.renalis zu bestimmen. Die Immunhistologie (CD31) wurde verwendet um die Dichte der Mikrogefäße darzustellen. Mit Hilfe der Fluoreszenzfärbung mit Hoechst H33342 konnte die Dichte der Mikro- und Makrogefäße und ihrer Kaliber dargestellt werden. Die anti-tumorale und anti-angiogene Wirkung des …
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Μελέτη της έκφρασης δεικτών του κυτταρικού κύκλου καθώς και αγγειογενετικών παραγόντων σε ασθενείς με ηπατοκυτταρικό καρκίνωμα, οι οποίοι υπέστησαν μερική ηπατεκτομή για θεραπευτικούς λόγους. Συσχέτιση με την μετεγχειρητική επιβίωση των ασθενών και τους κλασσικούς προγνωστικούς δείκτες της νόσου
… παράγοντα VEGF-A και του δείκτη αγγειογένεσης CD31 και την έκφραση των συστατικών του συμπλέγματος ΙΡP (ΙLK, β-parvin και PINCH), που εμπλέκονται στον έλεγχο του κυτταρικού πολλαπλασιασμού και της αγγειογένεσης. Παράλληλα, διερευνήσαμε την προγνωστική σημασία αυτών των παραγόντων αναλύοντας την …
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Effect of omega-3 polyunsaturated fatty acids on inflammatory biomarkers in chronic obstructive pulmonary disease
… The basal release of IL6, IL8, TNFα, and CD31 from PBMCs was significantly differing in COPD and HS groups compared to HNS group. Omega-3 PUFA (EPA and DHA) reduce IL-6, IL-8 and TNF-α release from PBMCs. The fatty acid composition of the erythrocyte membranes in patients group was …
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