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Showing 1 to 1 of 1 for “"CD25+CD4+ regulatory T cells"”.
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Functional characterization of rat CTLA-4 and CD25+CD4+ regulatory T cells
… and humans, rat CTLA-4 was detectable only in CD25+CD4+ regulatory T cells in unstimulated rats, and was upregulated in all activated T cells. Cross-linking rat CTLA-4 led to the deactivation of anti-TCR- and anti-CD28 stimulated (costimulation) T cell responses such as reduction in activation …