Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"CD166"”.
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CD166 modulates disease progression and osteolytic disease in multiple myeloma
… the skeleton. We previously reported that CD166 is a functional molecule on normal hematopoietic stem cells (HSC) that plays a critical role in HSC homing and engraftment, suggesting that CD166 is involved in HSC trafficking and lodgment. CD166, a member of the immunoglobulin superfamily …
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Akkumulation von T-regulatorischen Zellen im humanen Pankreaskarzinom durch selektive Tumorendothel vermittelte Adhärenz- und Transmigrationssteigerung
… durch Bindung von CD62L, ß-7 Integrin und CD166 an ihre tumorendothelial exprimierten Bindungspartner MAdCAM-1, VCAM-1, CD62-E und CD166 vermittelt. Die spezifische Blockade dieser Proteinbindungen mittels Antikörpern inhibierte in vitro und in vivo eine Treg-selektive Migration durch …
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Understanding Ontogeny and Optimizing Strategies to Promote Hematopoietic Engraftment Following In Utero Transplantation
… stem/progenitor cell (HSPC) subpopulation (CD166+CD34+), which we then found are also present within the adult-BM. We demonstrated that fetal CD166+CD34+ cells from different organs are functionally different, and also found that adult BM CD166+CD34+ cells are exclusively hematopoietic, and, …
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Development of 3D multicellular liver organoids derived from human induced pluripotent stem cells to model antiretroviral therapy induced liver injury
… and GSC) markers. Flow cytometry using EpCAM, CD166 and CD68 antibodies indicated that HLOs comprise of 60,4% EpCAM+ cells, 11,2% EpCAM-/CD166+ cells and 5% EpCAM-/CD68+ cells, respectively. HLOs exhibited high CYP3A4 enzyme activity compared to HepaRG 3D model. Proinflammatory (IL-6, IL-1β and …
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Resident angiogenic mesenchymal stem cells from multiorgan donor thoracic aortas
… of MSC i.e., CD44+, CD90+, CD105+, CD166+, CD34low, CD45- and revealed a transcript expression of stem cell markers, e.g., OCT4, c-kit, BCRP-1, IL6 and BMI-1. As previously documented using bone marrow derived MSCs, resident vascular wall MSCs were able to differentiate in vitro into …