Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"CD11c dendritic cells"”.
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NAD+-DEPENDENT SIRT1 REPROGRAMS CD11C+ DENDRITIC CELLS AND CD4+ T CELLS TO CONTROL IMMUNE POLARITY DURING SEPSIS
… In our model, SIRT1 activation acts through CD11c+ tolerogenic dendritic cells and their support of TGFβ and IL-10 secretions from CD4+ TReg cells as contributors to sepsis immunosuppression. That SIRT1 drives this innate and adaptive immune link is supported by the ability of SIRT1-specific …
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The Expression Of Connexin-43 By CD11c+ Dendritic Cells Is Required to Maintain CD4+ Foxp3+ Regulatory T Cell Population in Peripheral Lymphoid Organs
<p>Foxp3<sup>+</sup> regulatory T cells (T<sub>R</sub>) are an immunosuppressive subset of CD4<sup>+</sup> T cells that maintain homeostasis of the immune system. They are sustained by the interaction between the Major Histocompatibility Complex (MHC) molecules present on antigen presenting …
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Development of a Human Immune System from Hematopoietic Stem Cells in a Human/Mouse Xenogeneic Model
T cells play a central role in the development of immune responses. Patients lacking T cells due to genetic defects such as DiGeorge or Nezelof's syndrome and individuals infected with the human immunodeficiency virus are highly susceptible to infections and cancers. The lack of adequate in vivo …
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Ehrlichiosis: Understanding immune mechanisms that lead to the development of fatal disease
… syndrome marked by apoptosis of CD4+ T cells, a weak CD4 Th1 response, and overproduction of TNF-alpha and IL-10. C57BL/6 mice were inoculated intradermally or intraperitoneally with IOE, models that closely reproduce the pathology and immunity associated with tick-transmitted HME, or …
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Visualizing The Dynamics of Immune Surveillance In Brain Tumors By Intravital Multiphoton Microscopy
… of T cell surveillance in BTs. Resident immune cells of the myeloid lineage known as microglia are ubiquitous in the brain parenchyma while tissue-resident myeloid dendritic cells (DCs) known to activate T cells are relatively rare in the brain compared to DCs in other organs. Accumulating …