Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"CCR3"”.
-
Effector Cells and Mechanisms in Chronic Spontaneous Urticaria
… gating strategy for peripheral blood basophils (CCR3+CD123+ vs CCR3+CD63+ (p=0.0001), CD63+CD203c+ vs CCR3+CD123+ (p=0.0003), CD63+CD203c+ vs CCR3+CD63 (p=0.0001)). We then examined basophil variation using ImageStream® in healthy subjects. ImageStream® studies confirmed the difference in …
-
Dynamics of HIV coreceptors and their utilization by plasma and cerebrospinal fluid HIV-1 isolates
… a predominance of R5 phenotypes able to use CCR3 (R3R5) in CSF, also when X4/R5X4 virus dominated in plasma. R3R5 CSF variants correlated with late stage HIV-1 infection and high CSF viral load. CSF isolates from subtype C HIV-1 infected individuals generally used CXCR6, which also correlated …
-
ROLE OF THE MUCOSAE-ASSOCIATED EPITHELIAL CHEMOKINE (MEC/CCL28) IN THE MODULATION OF THE IMMUNE RESPONSE AGAINST VIRAL INFECTIONS
… surface. CCL28 is a chemokine that binds to CCR3 and CCR10 and potently recruits IgA-secreting plasma cells (IgA-ASCs) in the mucosal lamina propria. Virus-like particles (VLPs) are a novel vaccine approach based on non-pathogenic particles that mimic the structure of authentic virus …
-
The role of chemokines in the pathology of multiple sclerosis and other neuroinflammatory diseases
… within the lesion predominantly expressing CCR3, CCR5 and CCR8. <i>In vitro</i> studies confirmed the production of chemokines and the expression of chemokine receptors by isolated rat astrocytes and microglia following cytokine stimulation. The results of this study suggest chemokines play …
-
cDNA microarray Analysis Identifies Symptom-Associated Chemokine Genes in Behcet's Disease Mouse Model
… than BD inactive regions of skin inflammation. CCR3 was higher in PBMC of BD eye than BD inactive and BD skin. However, CCR7 was lower in BD skin relative to BD inactive and BD eye. The expression patterns of CCL19, a ligand of CCR7, was similar to CCR7 in lymph nodes. The expression patterns of …
-
The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function
… resembles that of the chemokine receptor, CCR3. Using a "humanized" hybrid rat CMKLR1/ChemR23 receptor as model, it was shown that the major determinants for HIV-1 and HIV-2 interaction with the receptor reside to a varying degree in the N-terminus and second extracellular loop, whereas the …
-
Die Bedeutung von Entzündung und reaktiven Sauerstoffspezies in der Intimahyperplasie
… und CXCR3B mit sich, sowie jeweils mit CCR2, CCR3, CCR5 und den Opioidrezeptoren MOR und KOR hin. Die getestete Methode des Fluoreszenz-Resonanz-Energietransfers (FRET) erwies sich jedoch als ungeeignet zur Untersuchung von CXCR3, da dieser in HEK293T-Zellen nicht korrekt transient exprimiert …
-
Acute tubulo-interstitial nephritis : clinical profile and pathogenic mechanisms
… CD4+ cells, CD8+ cells, CD68+ cells, eotaxin, CCR3, VCAM-1, IL-4 and eosinophil proteins. These results suggest that there is a Th 2 type of inflammatory and immune response in acute tubulointerstitial nephritis. Comparison between the infiltrating cells showed no significant difference (P …