Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"CCNE1"”.
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Low Molecular Weight Cyclin E Deregulates Dna Replication and Damage Repair to Promote Genomic Instability In Breast Cancer
… full-length cyclin E1 (FL-cycE, encoded by <em>CCNE1</em>gene). The resultant N-terminus deleted (40 amino acids) form of LMW-E is detected in breast cancer cells and tumor tissues, but not in normal mammary epithelial cells or adjacent normal tissues. Unlike FL-cycE, LMW-E drives mammary …
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Increasing IFN-[gamma] productivity in CHO cells through CDK inhibition
… we believe that the targeted knockdown of CcnE1 has the potential to induce growth arrest and improve total recombinant protein production The relationship between growth-arrested cell cycle phase and productivity is very poorly understood. In this work, we have used various CDK inhibitors …
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TRANSLATIONAL RESEARCH TARGETING BILIARY TRACT CANCER
… associations between certain immune markers and CCNE1 amplifications, gender, or tumor stage. Our results provide a foundation for larger scale immunogenomic studies of gallbladder carcinoma and may aid in the development of improved immunotherapies for this disease.</p> <p>To deepen our …