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Showing 1 to 1 of 1 for “"CCN5"”.
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Roles of CCN5 in regulating progression and therapeutic sensitivity of breast cancer
… Growth Factor-nephroblastoma-overexpressed 5 (CCN5) induces growth arrest of TNBC cells in-vitro and in xenograft tumors. Our studies show that after being secreted into the extracellular matrix, CCN5 binds to the α6β1 integrins of the cells leading to inhibition of the PI3K-AKT signaling …