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Showing 1 to 1 of 1 for “"CCL2-CCR2 signaling axis"”.
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Assessing The Outcomes of Blocking Ccl2-Ccr2 Signaling Axis On Breast Cancer Brain Metastasis
… breast tumor cells activates PI3K/NF-ƙB signaling and increases the secretion of the chemokine CCL2, which enhances the chemotaxis of CCR2<sup>+</sup> myeloid cells, a major subpopulation of bone marrow-derived myeloid cells (BMDMs), from peripheral blood into the brain tumor …