Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"CCK2R"”.
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RAF-1 kinase inhibitor protein-mediated cholecystokinin-2 receptor desensitization and extracellular signal-regulated kinase activation
… GPCR superfamily, Cholecystokinin-2 receptor (CCK2R) is a physiological receptor for gastrin (G17) and activates extracellular signal-regulated kinase (ERK) via the PKC activity. The inhibition of classical PKCs (cPKC, PKC-α,-β, and -γ) by Gö6976 indicated the augment in ERK …
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Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors
… The engineered cell line HEK293 CCK2R/hMC4R, which is genetically modified to over-express both the cholecystokinin 2 receptor (CCK2R) and human melanocortin 4 receptor (hMC4R), was used to test the multivalent constructs. The oligomers were rapidly assembled using …
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Development of new radiopharmaceuticals targeting the Cholecystokinin 2 receptor
Il percorso di studi sperimentali del presente Ph.D è stato incentrato sullo sviluppo di radiofarmaci innovativi e sulla loro valutazione preclinica. Il progetto è stato inquadrato all’interno della “filiera del radiofarmaco” nata a Catania grazie alla collaborazione instaurata tra il Center for …