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Showing 1 to 1 of 1 for “"CCDC47"”.
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Mechanisms of multipass membrane protein biogenesis
… consisting of the highly conserved proteins CCDC47 and Asterix. A diverse set of multipass membrane proteins show impaired biogenesis upon PAT complex depletion, despite correct topological insertion. Bio- chemical analyses demonstrate PAT complex engages nascent TMDs that contain unshielded …