Global ETD Search
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Showing 1 to 9 of 9 for “"CCAAT-Box"”.
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Die Regulation der humanen H3-Histongene
… untersucht. Im H3/m-Promotor wurden die TATA-Box, die proximale und distale CCAAT-Box und eine ATF-Box identifiziert. Im H3/k-Promotor wurden als wesentliche funktionelle Elemente die TATA-Box und die proximale und distale CCAAT-Box identifiziert. Der funktionelle Grundaufbau der H3‑Promotoren …
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Regulation der Genexpression und Promotoraktivität von RGS4 durch Leptin
… 63 bases upstream of the transcription start a CCAAT box, matching the consensus binding sequence of NF-Y (nuclear factor-Y, a CCAAT box binding factor) is located close to the TATA box. This part of the rat promoter bears a striking sequence similarity with the RGS4 promoter of other species. A …
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THE ALTERNATIVE SPLICING OF NF-YA REGULATES MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION
… subunit of NF-Y, NF-YA, recognizes and binds the CCAAT box motif, one of the most enriched DNA elements in enhancers and promoters of genes specifically active in ESCs. NF-YA exists in two different isoforms generated by Alternative Splicing of Exon 3. The short (NF-YAs) and the long (NF-YAl) …
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THE MESENCHYMAL IDENTITY OF NF-YA LONG ISOFORM: FROM VERTEBRATE EVOLUTION TO CANCER
… e dal regolatore NF-YA. NF-YA riconosce il CCAAT box sul DNA, un motivo diffuso nei promotori di importanti geni coinvolti nella proliferazione cellulare, nel metabolismo e nell’apoptosi. A causa delle funzioni che controlla, unitamente alla sua capacità di incrementare l’accessibilità …
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Expressionsanalyse des humanen Histonsubtyps H1x
… ein upstream positive element und eine TATA-Box, aber keine funktionelle CCAAT-Box. Dennoch unterscheidet sich das Expressionsmuster von H1x vom ebenfalls replikationsunabhängig exprimierten Replacementhiston H1.0. Dies wird durch Zellzyklusuntersuchungen und der vergleichenden Analyse der …
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NF-YA ISOFORMS ROLES IN CLAUDIN LOW CANCERS
… YC subunits. NF-YA recognizes and binds to the CCAAT box, a DNA element found enriched in the promoters of cancer-specific genes in several tumor gene expression profiles analyzed, including those of breast, colon, thyroid, prostate, and leukemia cancers. NF-YA is present in two major isoforms …
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STRUCTURAL ANALYSES OF TRANSCRIPTION FACTOR/DNA COMPLEXES: NFI-X AND NF-Y
… and (2) NF-Y, a histone-like TF that binds the CCAAT box in promoters of cell cycle genes. (1) The crystal structure of NFI-X was obtained in our lab a few years ago. However, no structural information regarding the DNA-binding mode of NFI-X was available until now. We were able to obtain a …
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Molecular characterization of a fusarium graminearum lipase gene and its promoter
… using a linker-scanning mutagenesis approach. A CCAAT box, a CreA binding site, and a fatty acid responsive element (FARE) were identified and confirmed to be responsible for FgLip1 basal expression, glucose suppression and fatty acid induction, respectively.
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Transcriptional regulation of the human alpha 2(I) procollagen gene
… is a ubiquitous factor which binds the inverted CCAAT box located between -92 and -80 (G/CBE) with an apparent Kd of 2.9nM. Complexes II and III both bind an adjacent DNA sequence between -78 and -67 (the CME) with Kd values of 4.2 and 3.5nM respectively. While the CCAA T boxes in the human and …