Global ETD Search
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Showing 1 to 9 of 9 for “"CBFB"”.
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Compatibility assessment for physical and mechanical properties of empty fruit bunch cement-bonded fibreboard
… may be used as an alternative for producing CBFB. Compatibility assessment for physical and mechanical properties of Cement-Bonded Fibreboard (CBFB) made of Empty Fruit Bunch (EFB) is important to identify the suitability of incorporating EFB into CBFB. However, there are known compatibility …
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Der Transkriptionsfaktor JunB in der zellulären Hypoxie-Antwort und in der Angiogenese : Entschlüsselung der übergeordneten Signalwege und Identifizierung und funktionelle Analyse des JunB-Zielgens CBFbeta
… Expression aufweisen. Der Transkriptionsfaktor CBFb, der im Verlauf der Arbeit genauer untersucht wurde, wird durch JunB und c-Fos induziert, wie Kotransfektionsanalysen mit einem Reporterkonstrukt zeigen, welches unter der Kontrolle des 1600 bp langen stromaufwärts von CBFb gelegenen …
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Analysis of senescence-like growth arrest induced by RUNX1 and its fusion derived oncoproteins
… fibroblasts that requires intact DNA binding, CBFB interaction and C-terminal transcriptional activation/repression domains. However, surprising differences were found between the major RUNX1 fusion oncoprotein derivatives. The N-terminal fusion protein TEL-RUNX1 fails to induce senescence …
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Mechanisms of Synthetic Lethality in Renal Cell Carcinoma
… techniques, I demonstrate that knockout of *CBFB* is lethal in cells lacking *VHL* through a mechanism which is independent of both direct CBF-β-RUNX binding and the high HIF activity of *VHL*-null cells. In addition, RNA sequencing and mass spectrometry reveal that CBF-β depletion causes a …
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Nachweis zytogenetischer Aberrationen nach Chemotherapie zur diagnostischen Früherkennung therapieassoziierter hämatologischer Neoplasien
… Fusionstranskripte t(8;21)/AML1/ETO, inv(16)/CBFB-MYH11, t(15;17)/PML-RARα und t(9;22)/BCR-ABL in 42 Leukapheresaten (33 Patienten mit NHL und 9 gesunde Spender) mittels konventioneller und Real-Time-PCR untersucht. Weder die Translokationen t(8;21), inv(16) noch t(9;22) konnten in dieser …
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EBV-Associated Gastric Cancer: From Initial Infection to Unique Therapeutic Approaches
… BYL719. Additionally, I found that loss of CBFB conferred resistance to BYL719 through up- regulation of the protein kinase PIM1 and defined the clinical utility of our data in the context of PI3K inhibition more broadly. The work outlined in this dissertation contributes to the study of EBV …
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The changing nature of supply chain management in the European grocery retail sector
Research in the field of distribution and logistics has been an area largely neglected by retail academics. While a considerable body of theoretical research has been undertaken on marketing channels, few researchers have investigated physical channels of distribution. This is surprising in view of …