Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 97 for “"CBF"”.
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Arterial Spin-labelled MRI Analyses to Advance Adolescent Bipolar Disorder Research and Clinical Applications
Cerebral blood flow (CBF) is foundational to brain function in health and disease. Through three distinct analyses, the aim of this thesis is to extend current understanding of CBF in adolescent bipolar disorder and to enable future understanding of CBF in other brain diseases. CBF measurement can …
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Identifying Patients at Risk for Hyperperfusion after Carotid Stenting Using CT Perfusion with Acetazolamide Challenge
… blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and percent change of CBF were investigated before, 1 day and 3 months after CS, with resting and ACZ-challenged CTP. Normal percent changes of CBV, CBF, and MTT were determined in 12 age and sex-matched normal …
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Mapping cerebral blood flow with speckle contrast optical spectroscopy
Cerebral blood flow (CBF) is a critical component of cerebral hemodynamics, yet the existing optical neuroimaging modalities to measure CBF do not have sufficient signal-to-noise ratio. Speckle contrast optical spectroscopy (SCOS) has been previously considered as an alternative approach to use …
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Identification of a ciliary defect associated with pulmonary nontuberculous mycobacterial disease
… abnormally low resting ciliary beat frequency (CBF) and abnormal CBF response to toll-like receptor (TLR) agonists. The depressed baseline CBF response in PNTM patient cells can be normalized ex vivo by augmenting the nitric oxide-cyclic guanosine monophosphate pathway without appreciable e ect …
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The effects of a 1.8 GHz continuous electromagnetic fields on mucociliary transport of human nasal mucosa
… the pathophysiology of ciliary beat frequency (CBF) during an EMF-induced change. Human nasal mucosa cells were exposed to a 1.8 GHz EMF (SAR= 1.0 W/kg), and CBF was analyzed using an optical flow technique with the peak detection method. The 1.8 GHz EMF-exposed group showed a decreased CBF when …
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Measurement of Cerebral Blood Flow Using Arterial Spin Labeling Magnetic Resonance Imaging
Cerebral Blood Flow (CBF) reflects the amount of blood perfusion in the brain, often defined as ml of blood per 100 gram of brain per minute. CBF is an important measure in understanding brain physiology and pathophysiology. Thus, it is important to establish a robust method suitable for …
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Vertex-Based Analysis of Cerebral Blood Flow and Fractional Amplitude of Low-Frequency Fluctuations (CBF-fALFF) Coupling in Moderate-to-Severe Traumatic Brain Injury During the First Year Post-Injury
… using a combined metric of cerebral blood flow (CBF) and fractional amplitude of low-frequency fluctuations (fALFF), a proxy for spontaneous neural activity. Using arterial spin labeling (ASL) and functional MRI sequences, CBF and fALFF were measured in 29 msTBI patients 3-, 6- and 12-months …
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Understanding the role of cerebrovascular health in cognitive aging: a multi-modal noninvasive human neuroimaging approach
… between aging and cerebral blood flow (CBF) in a group of older adults (ages 55-85). Using arterial spin labeling (ASL) to quantify CBF, we found that blood flow in the gray matter was positively correlated with CRF and negatively correlated with age (Zimmerman et al., 2014). Subsequent …
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Effects of Cerebral Blood Flow and Temperature on Executive Function During Moderate Hyperthermia
… be affected by changes in cerebral blood flow (CBF) as opposed to thermal perception changes. An end-tidal forcing system was used to maintain eucapnia and baseline CBF in the isocapnic trial during the hypocapnia-induced CBF reduction. Repeated measures analysis of variance indicated that an …
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Regional Low Cerebral Blood Flow Predicts Leukoaraiosis Development at 18 Months in Patients with TIA and Minor Stroke
… to investigate whether low cerebral blood flow (CBF) is associated with subsequent white matter hyperintensity (WMH) development in minor stroke and transient ischemic attack (TIA) patients. New WMH at 18 months were identified by comparing follow-up with baseline FLAIR, and regions of interest …
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Use of fluorescent micropsheres to measure coronary flow reserve in rat animal model
… damage to heart muscle. Coronary blood flow (CBF) is thus important to measure in experimental animal models of heart disease. A standard method to measure CBF uses tracer microspheres (O = 15 um) injected into the left ventricle that flow through coronary arteries but cannot pass through …
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ARTERIAL STIFFNESS AND CEREBRAL BLOOD FLOW AMONG OLDER ADULTS
… arterial stiffness and cerebral blood flow (CBF) with mild cognitive impairment (MCI). This study analyzes arterial stiffness and CBF as potential pre-clinical factors of AD in the Alzheimer’s Disease Prevention Participant Repository (ADPPR) cohort. There was a total of 91 participants from …
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Circadiane Periodizität des cerebralen Blutflusses : experimentelle und klinische Untersuchungen
… (SHT) durchgeführt. Der cerebrale Blutfluss (CBF) wurde bei Ratten mittels Laser-Doppler-Flowmetrie (LDF) kontinuierlich registriert. Es wurde eine Halterung entwickelt, mit der die Glasfaser so auf dem Schädel befestigt werden kann, dass die Bewegungsfreiheit der Tiere nicht eingeschränkt …
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Mechanisms of Synthetic Lethality in Renal Cell Carcinoma
… relationship between Core Binding Factor β (CBF-β) and pVHL. While CBF-β is critical for normal osteogenesis and haematopoiesis, little is known about its role in renal tissue. CBF-β classically stabilises the Runt related transcription factors (RUNX1-3) to improve their transcriptional …
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Reinforcement Learning Control for Mobile Robot Parking with Safety Constraints
… learning (RL) with control barrier function (CBF)-based methods to achieve safe autonomous vehicle control, focusing on parking with obstacle avoidance. We apply Deep Deterministic Policy Gradient (DDPG) methods for continuous control and evaluate policies across three Simulink environments of …
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Interferometric, acousto-optic modulated diffuse correlation spectroscopy @ 1064 nm (AOM-iDCS) toward higher sensitivity, non-invasive measurement of cerebral blood flow
… and continuously measures cerebral blood flow (CBF) is needed to properly manage treatment. Diffuse Correlation Spectroscopy (DCS) is an established optical technique that enables continuous, non-invasive, and direct measurements of CBF. The effectiveness of DCS in measuring CBF is hampered in …
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Framework for Assessing Integrated Water Resources Management in Latin America: Case Studies of Buenos Aires and São Paulo
… assessment tool, the City Blueprint Framework (CBF), which was designed to evaluate IWRM projects holistically. This research attempts to answer how well the CBF works to assess the sustainability of IWRM in both cities, and how well the cities are doing as part of the CBF indicator. World Bank …
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DEVELOPMENT OF IMPROVED ARTERIAL SPIN LABELING METHODS IN HUMANS AND ANIMAL MODELS
… tool in evaluating cerebral blood flow (CBF), with applications in clinical imaging for brain tumors and stroke, and as a research tool for brain injury and Alzheimers disease. Multi-TI ASL makes it possible to measure CBF and arterial transit time (ATT). First, multi-TI ASL is optimized …
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Expanding the role of functional mri in rehabilitation research
… These additional markers, cerebral blood flow (CBF) and cerebral blood volume (CBV) (and hence cerebral metabolic rate of oxygen (CMRO₂) modeling) are more specific imaging markers of neuronal activity than BOLD. The first aim of this dissertation assesses feasibility of complementing BOLD with …
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The impact of ischaemic preconditioning on cerebrovascular function in healthy individuals.
… the impact of RIPC on cerebral blood flow (CBF) or cerebrovascular function. The overall aim of this thesis was to assess, in healthy individuals, the impact of bilateral arm RIPC or SHAM on resting CBF, cerebrovascular reactivity, cerebral autoregulation, and autoregulation during …
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