Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CB1R antagonist"”.
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Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor
… through the type 1 cannabinoid receptor (CB1R) which is highly expressed in the human brain1,2. Defects in CB1R expression or endocannabinoid transmission have been associated with several neuropsychiatric disorders thus establishing CB1R as a potential drug target or biomarker of …
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Caratterizzazione del clofibrato agonista sintetico dei recettori dei proliferatori dei perossisomi (PPARα)in modelli animali di depressione ed ansia
… Acute administration of the specific PPARα antagonist MK886 (1 mg/kg, i.p) or the CB1 antagonist/inverse agonist SR141716A (1 mg/kg, i.p) did no antagonize the antidepressant-like effect induced by classical antidepressant drugs. In contrast the antidepressant-like affects of clofibrate were …