Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"CARMA3"”.
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Characterization of The Role of Carma3 In Endoplasmic Reticulum Stress-Induced Nf-Κb Activation
… domain (CARD)-containing proteins, CARMA3 and BCL10, play a crucial roles on ER stress-induced NF-κB activation by regulating IκBα kinase activity. Consistently, we observed that a physiological ER stress inducer, hypoxia, could activate NF-κB in a CARMA3-dependent manner. …
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Characterization of The Roles of Carma3 and Bcl10 In Virus-Triggered Rig-I/Mavs Signaling Pathway
… Herein, we revealed the important roles of CARMA3 and BCL10 in RIG-I/MAVS signaling pathway for the first time. CARMA3 or BCL10 deficient cells exhibited partially defective NF-κB activation but hyperactivation of TBK1-IRF3 signaling pathway upon ssRNA virus infection. It led to less …
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Taxonomic classification of metagenomic sequences
… lower taxonomic ranks. In this thesis we present CARMA3, a novel method for the taxonomic classification of assembled and unassembled metagenomic sequences that has been adapted to work with both BLAST and HMMER3 homology searches. CARMA3 accepts protein-encoding DNA sequences, protein sequences, …
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The Roles of Malt1 In Nf-Κb Activation and Solid Tumor Progression
… MALT1, together with its interaction partners CARMA3 and BCL10 (also known as the CBM complex), is required for HER2-induced NF-κB activation. Consistently, the CBM complex contributes to malignant phenotypes in breast cancer cells, including proliferation, survival, migration, invasion and …