Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"CAM-Assay"”.
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Development of the chick chorioallantoic membrane (CAM) xenograft model to study metastasis and angiogenesis in autophagy deficient osteosarcoma cells
… prognosis. The Chicken Chorioallantoic Membrane (CAM) assay has emerged as a valuable tool, offering an easy, inexpensive and rapid alternative for direct visualisation of tumour development. This study aimed to design and optimise the CAM assay as a physiologically relevant model to understand OS …
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Development of the chick chorioallantoic membrane (CAM) model to assess tumour growth and drug response in osteosarcoma and bladder cancer
… and apply the chick chorioallantoic membrane (CAM) assay, an innovative, cost-effective in ovo model that allows visualisation of tumour growth in an in vivo-like environment while minimising animal suffering. While CAM studies have shown promise in osteosarcoma research, their application in …
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Etablierung von Methoden zur Bioevaluation antitumoraler Naturstoffe, Metabolite und Analoga
… mit GSH eingeht (siehe 3.4). Der Alkylierungsassay mit Aceton liefert nur für farblose Verbindungen verlässliche Ergebnisse. Bei den getesteten Illudinderivaten 27 konnte zwar ein Alkylierungspotential gemessen werden, doch stellt deren vorhandene Eigenabsorption einen gewissen …
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Investigating the Anti-inflammatory Activity of Honey
… component, creating an in vitro assay to measure the anti-inflammatory activity of individual honeys and attempting to identify and characterise the component(s) responsible for the activity. A cell line (THP-1) was selected for this study based on its macrophage phenotype upon …
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Vaskuläre Progenitorzellen und embryonale Angiogenese
… Empfängern (7.-14. Entwicklungstag) wurden die CAM mit Transplantat sowie ausgewählte Organe des Empfängers mittels BrdU-Immunhistochemie und Lichtmikroskopie ausgewertet. <br>Zunächst war festzustellen, dass die BrdU-Markierung des KM nicht toxisch und Langzeit-stabil bis zu 19 Tagen ist. …
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Synthese von Iridoidglykosiden in Pflanzen und Gewebekulturen
… S. nodosa und P. lanceolata. Im in vivo CAM-Assay am Hühnerembryo konnte für Harpagosid und Catalpol keine antiangiogene Wirkung nachgewiesen werden.
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Modelling Embryonic Haematopoiesis Using In Vitro State-of-art Gastruloid Culture
… by a combination of markers in flow cytometry assays (Flk-1, c-Kit, CD41 and CD45). Concomitant use of cytokines VEGF and FGF2 can facilitate the emergence of cells with the property of haemogenic endothelial cells, pro-HSCs and type 1 pre-HSCs from 96 to 144 hr. Applying Shh, Flt-3l, TPO, and …
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Molecular and bio-analytical characterisation as a means to understand genetic diversity within Kenyan Aspergillus flavus strains
… served as the basis for an in vitro biocontrol assay. Out of 37 isolates identified, nitrate non-utilizing auxotroph’s complementation test revealed 20 vegetative compatibility groups. These groups were further designated using the prefix ʻʻKVCGʼʼ, where ʻʻKʼʼ represented Kenya and consequently …
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Surface Functionalisation of Metal-Organic Frameworks for Biomedical Applications
… the Hen’s egg test-chorioallantoic membrane (HET-CAM) assay, showing increased biocompatibility, sustained release of the cargo, and enhanced performance compared to the free drugs at high concentration. Finally, a novel targeting mechanism based on lectin, a targeting protein, and a DNA bridge …