Global ETD Search

Estrogen Receptor Ligands and Regulation of Gene Expression

Sheng, ShubinUniversity of Illinois at Urbana-Champaign2015

Keratin13 (KRT13) and calcitonin receptor (CALCR) gene expression is differentially regulated by estradiol (E2) and the selective estrogen receptor modulators (SERMs) tamoxifen and raloxifene. KRT13 is a cytoskeleton protein while CALCR mediates the biological effects of calcitonin. These two genes …

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Impact of genetics and phosphorous nutrition on bone metabolism

Hittmeier, Laura2005

… dietary treatment affected the expression of CALCR (P<0.05), VDR (P<0.04), IGF1 (P<0.11), and IGFBP3 (P<0.06). There was also a trend of increased IL6, TFIIB, and S0X9 expression with P deficiency in HB, but not LB, pigs. A trend of increased expression of OXTR was seen in P deficient animals …

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Identification of Common and Separate Mechanisms Governing Circadian Locomotor Activity and Body Temperature

Shimatani, HiroyukiKyoto University2021

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Activation mechanisms of non-class A G protein-coupled receptors

Bansal, PrateekUniversity of Illinois Urbana-Champaign2025

G protein-coupled receptors are central to mediating homeostasis across a plethora of biochemical signaling pathways across the entire body and are one of the most important classes of drug targets. While the majority of the recent literature on GPCRs focuses on Class A GPCRs, the structural and …

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