Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 28 for “"CADD"”.
-
CADD : on reorganizing the practice of architecture
… While a small computer team, composed by CADD specialists, initially supported the computer facilities in architectural practice, it is particularly important to demonstrate that every professional should be able to access, and work directly on the computer, adding to the dissemination of …
-
Developing criteria for PC-CADD evaluations : a case study
While the usefulness of CADD in the production stages of the architectural design process is now widely acknowledged, its true benefits for earlier, schematic design phases remain unclear. Due to the very subjective nature of that process and the complexity of its overlap with other design stages, …
-
Perceived importance of national occupational CADD skill standards among faculty of NAIT accredited institutions
1 PDF file (vii, 114 pages)
-
Attitudes of interior design students toward creativity in design problem solving using CADD versus conventional drafting tools
… creativity in design problem solving using CADD versus conventional drafting tools and to research whether CADD stifles or encourages students' creativity in that manner. Students' level of CADD perf onnance, past experience with CADD or other microcomputer software and level of CADD …
-
Development of N-domain selective Angiotensin-I Converting Enzyme (ACE) inhibitors using Computer Aided Drug Discovery (CADD)
… inhibition. Three computer aided drug discovery (CADD) approaches were pursued to design N-domain selective drug-like ACE inhibitors (ACEi) with an acidic P₂ functional group that would confer N-domain selectivity via an interaction with Arg381 in the S₂ subsite. Firstly, a fragment-based …
-
Management of standard graphic symbols in a computer-aided design and drafting environment using neural network approaches
Computer-Aided Design and Drafting (CADD) systems have become prevalent for producing building design drawings. An ultimate goal of CADD systems is to automate analyses and communication of high-level design information extracted from CADD drawings, a difficult task because of the lack of CADD …
-
The Effects fo a Changing Technical Graphics Curriculum
… industries. Computer Aided Drafting and Design (CADD) has had a tremendous impact on the production of technical graphics. Within vocational and technical education, traditional manual drafting curricula continues to be the primary teaching method for beginning technical graphics classes. A study …
-
The effects of 3-dimensional CADD modeling software on the development of the spatial ability of ninth grade technology discovery students
… instructional methods utilizing Pro/Desktop® 3-D CADD solid modeling software. Participants were students in Mississippi schools operating on a 4 x 4 block schedule during either fall or spring semesters during the 2005-2006 school year, and a control group of students whose schools did not offer …
-
Biochemical Characterization of Self-Sacrificing P-Aminobenzoate Synthases from Chlamydia Trachomatis and Nitrosomonas Europaea
… Protein Associating with Death Domains (CADD) due to its established role in host mediated apoptosis, while the crystal structure showed an architecture similar to know diiron oxygenases. However, we provide evidence of a moonlighting function in pABA synthesis. Isotopic labeling …
-
Computer utilization in interior design: a comparative study of attitude, application, and equipment usage in 1985 and 1988
… were statistically significant indicate that CADD (Computer-Aided Design and Drafting) users reflect more positive opinions towards computers than non-CADD users. Overall, more computers are being utilized in 1988 than 1985. Both microcomputers and mini/mainframe computer usage has increased. …
-
Protein and Water Modeling in Computer-Aided Drug Discovery
<p>The field of Computer-Aided Drug Design (CADD) is continuously evolving to improve protein modeling, a crucial step in the drug discovery process. However, limitations exist in how CADD accounts for the various configurations a protein can adopt due to different rotamer and protonation states of …
-
Re-imagining Drug Discovery with Quantum Computing: A Framework and Critical Benchmark Analysis for achieving Quantum Economic Advantage
… powered by computer-aided drug discovery (CADD). Drug discovery companies are rapidly transitioning to the use of artificial intelligence to expedite and enhance research and development. However, many of the classical AI use cases scale exponentially fast and face computational power …
-
Determining and Exploiting Common Interactions in the Peptidyl Transferase Center for Enhanced Derivative and Bidentate Design
… resistance. However, computer aided drug design (CADD) using ribosome crystal structures presents several challenges and is underutilized in the field. In this work we establish a successful protocol for antibiotic redocking and docking within the high interest sites of the peptidyl transferase …
-
Three-Dimensional (3D) pharmacophore-based identification of possible ATP-synthase inhibitors for mycobacterium tuberculosis (Mtb)
… technologies of computer-aided drug discovery (CADD) has proven to be a powerful tool in reducing costs, as well as time, and ensures the efficiency of lead compound identification. CADD can be divided into two categories; structure-based (SB) and ligand-based (LB) drug discovery. The categories …
-
Rational Development of New Inhibitors of Lipoteichoic Acid Synthase
… still remains. Computational-aided drug design (CADD) is a cost-effective and useful approach that has been widely integrated into the drug discovery process. The protein eLtaS lends itself to be a good target for CADD since its crystal structure and a known inhibitor (with limited …
-
Structure-based approaches applied to the study of pharmaceutical relevant targets
… and modern drug discovery approaches. Indeed CADD is useful to improve and speed up the detection and the optimization of bioactive molecules. The present study is focused on the application of structure-based approaches to the study of pharmaceutical relevant targets. The introduction …
-
Refining computer-aided drug design routes for probing difficult protein targets and interfaces
… take years to study. Computer-aided drug design (CADD) routes can support the areas of drug discovery that are considered difficult to explore with experimental techniques. In this work, we provide research practices that are easily adaptable and translatable to other difficult protein targets and …
-
Design of Selective Plasmodium falciparum Kinase Inhibitors using Computer-Aided Drug Discovery
… study was to use computer-aided drug design (CADD) methods to rationally design and accelerate the identification of P. falciparum kinase inhibitors. The foremost part of this project was focused on the design and synthesis of novel analogues of the anticancer human mammalian target of …
-
Improving Dbnsfp
… indel annotation based on gene models, including CADD, SIFT, and PROVEAN. All those scores can be calculated on-the-fly after installing resources locally. A Docker implementing the indel annotation and deleteriousness prediction has been developed and ready to be deployed from the cloud.</p>
Page 1 of 2