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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 158 for “"CA1"”.

  1. Estrogenic modulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses

    Clements, LeighUniversity of Dundee2020

    … estrogen at hippocampal Schaffer-collateral (SC)-CA1 synapses has been described in detail and at these synapses, estrogen can rapidly potentiate excitatory synaptic transmission (Oberlander and Woolley., 2017). The actions of estrogen at the anatomically distinct Temporoammonic (TA)-CA1 synapse …

    dundee Repository record

  2. BDNF-TrkB Signaling in Efficacy of CA3-CA1 Synapses and Ketamine-Mediated Antidepressant Effects

    Lin, Pei-Yi2022

    The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.

    utswmed Repository record

  3. Die Wirkung von Serotonin-Wiederaufnahmehemmern auf Ca 2 +-Ströme in hippocampalen CA1 Pyramidenzellen der Ratte

    Haug, Verena Judith, Berger, Mathias

    … die Wirkung von SSRI auf Ca2+-Ströme in CA1 Pyramidenzellen der Ratte durch Ganzzell-Ableitungen mit Patch-Clamp Technik. <br>Es zeigte sich, dass SSRI (Fluoxetin, Fluvoxamin, Paroxetin, Sertralin) in verschiedenem Ausmaße Ca2+-Kanäle blockieren. Citalopram zeigte keinen Effekt auf …

    freiburg-diss Repository record

  4. Conditioned Arc expression in CA1 of the rat hippocampus supports long-term memory for temporal events

    McHugh, Rebecca R., University of Lethbridge. Faculty of Arts and Science2022

    lethbridge

  5. THE EFFECT OF SPILLOVER ONTO IONOTROPIC GLUTAMATE RECEPTORS AT THE SCHAFFER-CA1 SYNAPSE IN HIPPOCAMPAL SLICE

    Hoffman, Katie Marie

    … EAAT1-3 in synaptic transmission at the Schaffer-CA1 synapse in acute hippocampal brain slices. My results demonstrated that transport block by L-TBA resulted in glutamate spillover and activation of NMDARs. Further investigation showed that L-TBA-mediated activation of NMDARs was facilitated by …

    montana-tech Repository record

  6. THE EFFECT OF SPILLOVER ONTO IONOTROPIC GLUTAMATE RECEPTORS AT THE SCHAFFER-CA1 SYNAPSE IN HIPPOCAMPAL SLICE

    Hoffman, Katie Marie

    … EAAT1-3 in synaptic transmission at the Schaffer-CA1 synapse in acute hippocampal brain slices. My results demonstrated that transport block by L-TBA resulted in glutamate spillover and activation of NMDARs. Further investigation showed that L-TBA-mediated activation of NMDARs was facilitated by …

    montana Repository record

  7. Role of galanin in synaptic transmission and plasticity in the CA1 area of the rodent hippocampus

    Coumis, UraniaThe University of Edinburgh2005

    … on synaptic transmission and plasticity in the CA1 area of rodent hippocampus and (2) investigation of glutamatergic synaptic plasticity in galanin knockout mice and their wild-type littermates. Exogenous galanin induced a dose-dependent increase in the slope of baseline fEPSPs, which appeared …

    edinburgh Repository record

  8. Temporal synchronization of CA1 pyramidal cells by high-frequency, depressing inhibition, in the presence of intracellular noise

    Kunec, Stephen A.

    The Sharp Wave-associated Ripple is a high-frequency, extracellular recording observed in the rat hippocampus during periods of immobility. During the ripple, pyramidal cells synchronize over a short period of time despite the fact that these cells have sparse recurrent connections. Additionally, …

    njit Repository record

  9. Modulation as an Acidosis-Evoked Current by A1 Adenosine Receptors in the CA1 Region of the Mouse Hippocampus

    Galanis, Victor Chris2010

    Acidosis, along with hypoxia and hypoglycemia are immediate metabolic consequences of reduced blood flow to the brain. Acidosis exacerbates ischemic brain injury by activating non-selective cation currents that induce neuronal damage in a calcium-dependent manner, independent of glutamate receptor …

    utswmed Repository record

  10. Hippocampal output to neocortex: Examination of the electrophysiological and plastic properties of CA1 projections to the perirhinal cortex

    Kealy, JohnNational University of Ireland Maynooth2009

    … hippocampal-neocortical projection. The CA1 to perirhinal cortex projection has been previously shown to sustain LTP; by stimulating the area CA1 and recording in the perirhinal cortex, we show that it can sustain short- and long-term changes in synaptic plasticity. Additionally we …

    maynooth Repository record

  11. Leptin induces a novel form of long-term potentiation at the direct cortical input to hippocampal CA1 synapses

    Luo, XiaoUniversity of Dundee2013

    … hippocampal synaptic plasticity at hippocampal CA1 synapses via activating postsynaptic NMDA receptors. In particular, leptin induces a long-term (P5-8) or transient (P11-18) depression of synaptic transmission that depends on GluN2B subunit-containing NMDA receptors in juvenile hippocampus, …

    dundee Repository record

  12. Classification of Neuronal Nicotinic Acetylcholine Receptors in Rat CA1 Hippocampal Interneuron Subpopulations Defined by Calcium-Binding Protein mRNA Expression

    Burgon, Richard M.2006

    … stratum radiatum or stratum oriens within the CA1 region of rat hippocampi was analyzed using quantitative real time RT-PCR. Eighty-seven percent of the interneurons examined expressed CaBP mRNA. Parvalbumin mRNA was detected in 64%, while calbindin and calretinin expression was detected in 26% …

    byu Repository record

  13. Knockout of the glutamate transporter GLT-1 specifically from neurons drastically alters transcriptome profiles in CA3, CA1, and Striatum

    Houston, Alexander Cory WrightMassachusetts Institute of Technology2015

    … pyramidal neuron axon terminals within CA3 and CA1 as well as in cortical layer V pyramidal neuron axon terminals within striatum. The specific functions of GLT-1 in axon terminals in regulating glutamate homeostasis and synaptic transmission are unknown; in order to investigate these functions, …

    mit Repository record

  14. Modulation of long-term potentiation by the glycine site of N-methyl-D-aspartate receptor in rat hippocampal CA1 pyramidal cells

    Krasteniakov, NicholasCarleton University2004

    carleton Repository record

  15. Age-dependent regulation of hippocampal excitatory synaptic transmission by leptin

    Mcgregor, GemmaUniversity of Dundee2018

    … age-dependent manner at Schaffer collateral (SC)-CA1 synapses (Moult and Harvey, 2011). In addition, recent evidence indicates that leptin can also regulate synaptic transmission at the anatomically distinct input to CA1 neurons, the temporoammonic (TA) synapse (Luo et al., 2015). Therefore, the …

    dundee Repository record

  16. Insulin Modulates Synaptic Transmission and AMPA Receptor Trafficking Via Insulin Receptor Signaling Molecule In Region CA1 of the Juvenile and Mature Hippocampuss

    Wrighten, Shayna

    … produces long term depression (LTD) in region CA1 of the juvenile and mature rat hippocampus. Using western blot analysis and field potential slice electrophysiology, I performed studies to further investigate the mechanisms underlying insulin-LTD. In addition, I examined the age-dependent …

    south-carolina Repository record

  17. CaMKII at a central synapse : α-calcium/calmodium protien kinase II and synaptic plasticity at CA3 Schaffer collateral -- CA1 synapses in the mammalian hippocampus

    Hinds, Heather L., 1969-Massachusetts Institute of Technology2001

    … (LTP) of synaptic transmission at the CA3-CA1 hippocampal synapse is a model synaptic plasticity mechanism that may underlie hippocampal dependent learning and memory. Inhibition of post-synaptic calcium/calmodulin protein kinase II (CaMKII) has been shown to block LTP, and a global …

    mit Repository record

  18. Ribonomic Control During Global Brain Ischemia And Reperfusion

    Wang, Haihui2014

    … the selective delayed death of hippocampus CA1 neurons after transient global brain ischemia. The main findings are summarized:</p> <p>1. The main form of ELAV protein family member detected in CA1/CA3 in Hu protein immunoprecipitation and polysomes was HuB (Rel-N1). HuB is present in …

    wayne-thes Repository record

  19. Cannabinoid regulation of excitatory synaptic transmission at hippocampal synapses

    Farah, AdhamUniversity of Dundee2021

    … synaptic transmission at different hippocampal CA1 synapses.<br/><br/>In this study, standard extracellular recordings were used to examine the effects of different selective CB1R agonists on excitatory synaptic transmission at the temporoammonic (TA) input to CA1 neurons and at the Schaffer …

    dundee Repository record

  20. Functional Characterization of Hippocampal Synapses in a Mouse Mutant of the Dystrobrevin Binding Protein 1 (DTNBP 1) Gene

    Orozco, Ian Jay2011

    … basal synaptic transmission at the CA3-CA1 connection of juvenile mice, which has not been reported in the literature. To understand this novel phenomenon in better detail, a series of experiments was performed in hippocampal slices and cultures to functionally dissect the specific …

    columbia-diss Repository record

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