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Showing 1 to 20 of 21 for “"C910 - Applied biological sciences"”.
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The characterisation of nickel resistance in sewage-borne enterobacteriaceae
This thesis is a continuation of experimental work conducted by Pickup el al. (1997) analysing nickel resistant bacteria isolated from effluent discharged from a sewage outfall in the Lake District, Cumbria. Its aim is to further characterise the nickel resistance determinant ftom Enterobacter …
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Socioeconomic factors and hypertension in Al-Ain, UAE
… using the Statistical Packages for Social Sciences (SPSS). Student's t-test, Mann-Whitney test, chi-square test and ANOVA test were used to assess the relationship between these factors and the incidence hypertension. SBP and DBP. For the Arab expatriates, the present study found a …
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The effects of ageing and streptozotocin (STZ) - induced diabetes mellitus on the rodent parotid gland
Xerostomia (dryness of the mouth) is a prevalent condition amongst elderly and diabetic populations which leads to marked alterations in oral health. The parotid glands play major roles in maintaining salivary secretions to assist in the lubrication and protection of the oral cavity and in …
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Biofilm formation in clinical and laboratory strains of Escherichia Coli and Campylobacter Jejuni
Biorilms are structured communities of bacterial cells enclosed in a self-produced polymeric matrix that are adherent to an inert or living surface. Their growth on the surface of catheter lines, artificial joints and other surgical implants is of major medical concern. As many laboratory strains …
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The epidemiology of congenital hypothyroidism in the United Arab Emirates
… of CH in the UAE in terms of assessment of biological and environmental components and their significance in the relatively increased incidence of the disease in this community compared to the worldwide incidence (1:30004000). This study employed radioimmunoassay technique used by the …
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Expression of the multi-drug efflux genes acrAB of Escherichia coli
… mRNA levels; however the method can readily be applied to the study of other E. coli genes. The method was uniquely applied to the investigation of acrAB transcription throughout the growth cycle of E. co/i during batch culture in LB broth, in order to ascertain the patterns of expression for …
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Hormonal regulation of phosphatidylcholine metabolism in Apium graveolens
Previous studies using plant growth inhibitors and gibberellic acid led to the hypothesis that two pools of phosphatidylcholine exist within the plant cell; one capable of producing signals involved in cell proliferation and the other capable of releasing signaling molecules which facilitate cell …
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Gene regulation and hypertroipc responses in age-matched control and STZ-treated rats
Calcineurin is an endogenous calcium dependent protein which is involved in the development of cardiac hypertrophy. This study investigated the role of calcineurin in the streptozotocin (STZ)- induced rat heart compared to their age-matched healthy control hearts. The calcineurin signal process is …
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Differential regulation of cytokine secretion in multiple sclerosis
Multiple sclerosis (MS) is the most common autoimmune inflammatory demyelinating disorder of the human nervous system affecting nearly 1 million people worldwide every year. Current treatments for first-line nontoxic therapy of the relapsing-remitting form of the disease are two forms of …
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Identification of biological markers for neuropsychiatric disorders
Geriatric population is a rapidly growing segment of western communities. The need of management of this specifically vulnerable group of individuals has led to numerous studies concerning early detection of factors, which could be of importance for the course and prognosis of disorders in the …
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The neurobiology of central dopamine and progesterone in the reproductive cycle of the ring dove (Streptopelia risoria)
The ring dove (Streptopelia risoria) is a usefUl animal model for the identification of neural and hormonal determinants of reproductive behaviours. Studies were undertaken to investigate the role of dopamine and progesterone in the expression of sexually differentiated patterns of behaviours …
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A study of gene expression in human normal and carcinogenic cell lines using qRT-PCR
The susceptibility of human lungs to carcinogens depends on the metabolic balance between activation and detoxification pathways, though for the tumour to develop depcnds on activation of cell immortalisation pathway. The correlation of these pathways has not been reported. The present study …
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Identification and characterisation of cardiolipin autoantibodies
The aim of this study was to develop a method to isolate and identify anticardiolipin antibodies found in human serum samples obtained from patients with antiphospholipid syndrome (APS) APS is a disorder with clinical manifestations that include venous and arterial thromboembolism, …
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A study of a cyanobacterial bloom in the Albert Dock in Preston, Lancashire, UK
… at the time of sampling. These techniques were applied to assess the efficacy of a biocide preparation. A consensus of re-growth and viability experiments of biocide treated samples show that the concentration at which the stabilised biocide inhibited the growth of Planktothrix (Osdilatoria) …
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Effects of momordica charantia fruit juice on experimental diabetes and its complications
Momordica charantia fruit is traditionally used as a vegetable in the Indian subcontinent and is claimed to have hypoglycaemic effects in human and experimental diabetes. The oral administration of M. charantia fruit juice was investigated for its effects in streptozotocin (STZ)-induced diabetes in …
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Localisation of sex steroid receptors and effect of Tamoxifen upon glioma cell lines in vitro
Gliomas are the most common form of primary tumour of the central nervous system with a lethality rate approaching 80% in the first year of diagnosis. Their highly invasive nature renders local therapies such as surgery and radiation ineffective, whereas novel approaches such as immunotherapy are …
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Detection of campyloabacter jejuni and campylobacter coli in high risk foods and environmental waters using the polymerase chain reaction
… RT-PCR in bacteria established. The assays were applied to the detection of heat-killed and chlorine-killed cell suspensions with diflèrentiation between viable and heat-killed cells being demonstrated. However, problems with target-dependent variations in the halilives of the mRNA targets were …
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The role of EHIDA Cholescintigraphy in the diagnosis of Human Sphincter of Oddi Dysfunction
The aim of the study was to review the efficacy of a nuclear medicine diagnostic procedure at a local district general hospital. This test, called cholescintigraphy, aims to be able to diagnose patients who have problems with the release of bile from the bile duct. In particular some patients have …
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Factors controlling the expression of central progesterone receptors
Progesterone, a steroid hormone is closely associated with a variety of behavioural and neuroendocrine functions. Studies were undertaken to identify the control of progesterone receptor (PR) expression in avian brain tissue. In the first study, glial cells taken from newly hatched ring doves …
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