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Showing 1 to 4 of 4 for “"C700 - Molecular biology, biophysics & biochemistry"”.
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Identification of Circulating MicroRNAs as Biomarkers in Glioblastoma
MicroRNAs (miRNAs) are small RNA sequences 22-25 nucleotides in length which play a role in post-transcriptional gene regulation by binding to target mRNA sequences preventing translation. Changes in miRNA expression can contribute to disease pathogenesis, including gliomagenesis. The release of …
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The Identification and Validation of Novel Aptamers to Glioma
Glioma is a cancer derived from transformed glial cells; these tumours are often invasive and display a heterogeneous cell population, with various phenotypes. Current treatment modalities for glioma are ineffective, with minimal improvement to overall patient survival over the last decade. …
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Can curcuminoids be more effective than sulfasalazine for the treatment of rheumatoid arthritis?
Rheumatoid Arthritis (RA) is a debilitating, chronic autoimmune disease leading to progressive joint destruction. Current treatment includes methotrexate and sulfasalazine, however, side effects and tolerability are major limitations. Curcumin is a natural polyphenol obtained from Curcuma Longa …
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Can curcumin improve the methotrexate based treatment for rheumatoid arthritis?
Rheumatoid arthritis (RA) is an autoimmune disorder characterised by its varied and unpredictable origin, eventual destruction of cartilage and bone and the perpetual length of treatment involved. Even though significant developments have taken place over the past couple of decades in the …