Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"C3d"”.
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Potentiating Antibody Therapy by Targeting Complement on Cancer Cells
… complement activation fragments, especially C3d. Indeed, C3d opsonized CLL cells persisted for weeks in circulation. (Beurskens et al., 2012). At final restaging after combined ofatumumab and chemotherapy treatment, many patients had CD20 negative, but C3d positive disease. This suggests that …
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Studies on the Complement Receptor of a Human Lymphoblastoid Cell Line
… was used to investigate a surface marker, the C3d receptor. A method for cloning these cells at a relatively high efficiency was developed and C3d receptor bearing (CR+) and receptor free (CR-) subclones isolated. Receptor bearing cells were identified by their capacity to bind to complement …
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Membrane-Bound Immunomodulators As Adjuvants In A Cell Culture-Based Avian Influenza Vaccine
… tested in a chicken model using membrane-bound C3d, GMCSF, IL2 and IL4 as adjuvants. GMCSF adjuvanted vaccines delivered subcutaneously and C3d adjuvanted vaccines delivered subcutaneously and intranasally resulted in significantly higher antibody titers than vaccinating with inactivated virus …
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Development and clinical bench testing of a Matlab based, user friendly, deployable software application for automatic batch processing of fully instrumented three-dimensional human movement biomechanics data
… capture systems use a standard file format (C3D) to output data. Current methods for reading and interpreting these files, to acquire the information commonly used in reporting gait, are complicated, time consuming and require expensive licenses and training. A utility with a straightforward …
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Targeting the CD19/CD21 complex on B cells in the mixed lymphocyte reaction
… functions. Furthermore, the combination with C3d adjunction would direct antigensto CD21-mediated uptake for class II MHC presentation, taking advantage of the incapacity to derive any costimulatory activities as part of this process. The subset of B cells hereby generated would therefore have …
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The Impact of Ventricular Assist Device Prior to Transplantation on Morphological Parameters in Cardiac Allografts /// Въздействие на вентрикуларните помощни устройства преди трансплантация върху морфологичните параметри при сърдечните алографи
… of MCS on cardiac AMR with regards to capillary C3d and C4d depositions. Regarding the functional parameters, both acute cellular rejection (ACR) and an increase of interstitial fibrosis (IF) often correlate with impaired ventricular function. The innate immune system, in particular macrophages, …
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Circulating immune complexes in acute rheumatic carditis
… as well as the complement breakdown product C3d, were measured.
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The role of human CD23 in lgE homeostasis & allergic disease
… surface of human B cells, in a similar way to C3d-antigen complexes and mIgM, to upregulate IgE synthesis and provoke allergic responses.<br/>To test this hypothesis, purified tonsil B cells were stimulated with IL-4 and anti-CD40 to induce class switching to IgE in vitro. mCD23 was …
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The role of Moraxella catarrhalis outer membrane proteins in pathogenesis
… fragment in the both UspA1 and A2. Importantly, C3d fragment of C3 has been found responsible for the binding to UspA1/A2. The UspA2 has been demonstrated to inhibit both the classical and the alternative pathways of the complement. The C3 binding by M. catarrhalis strongly correlated with serum …