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Showing 1 to 18 of 18 for “"C100 - Biology"”.
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Biology of adult human normal and leukaemia CD133+ stem cells
Recently, CD133 has been used extensively as a marker for identification of stem cells from human normal and malignant tissues. Human normal CD 133+ stem cells are capable of multilineage in vitro and in vivo differentiation providing a novel source of stem cells for regenerative therapy, whereas, …
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Cellular mechanism of contractile dysfunction in diabetes-induced cardiomyopathy
This study investigated the cellular mechanism(s) that underlying contractile dysfunction in the streptozotocin-induced (type 1) diabetic cardiomyopathy compared to age-matched control heart. Human and animal studies have shown that diabetes mellitus can be associated with altered cardiac function …
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Effect of progesterone on secretagogue-evoked secretory responses in the isolated pancreas
The study investigates the effect of the neurotransmitter acetylcholine (ACh), the gut hormone, cholecystokinin-octapeptide (CCK-8) and the steroid hormone, progesterone on amylase release and preliminary data on ion (potassium (K), sodium (Nat), magnesium (Mg 2+) and calcium (Ca 2+) transport in …
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The deterioration of concrete by heterothrophic bacteria and fungi
The aim of this investigation was to design and develop a novel decontamination process for concrete, which could harness the deteriorative effect of various microorganisms found within the natural environment by a process known as biodecontamination. Whilst the majority of existing research into …
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The effect of bis(tributyltin) oxide on wood inhabiting microfungi
The influence of above ambient temperatu$bn the activity of Tn.B.T.O. was investigated. Above ambient temperature is likely to accelerate the breakdown of the preservative inPinur* syIyesjjjA combination of antioxidant and preservative effects some reduction in breakdown suggesting that oxidative …
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The effect of exercise on the utilization of dietary energy by the laboratory rat
The main purpose of this investigation was to examine the effect of enforced moderate exercise, in combination with various dietary regimes on the efficiency of energy storage, mobilization and utlization in the male Wistar rat. The experimental approach adopted was to combine the carrying out of …
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Identification and characterization of glial and neuronal cells in vitro and in bone marrow
This study attempts to identify and characterize glial cells and neuronal cells in avian brain and mammalian bone marrow, respectively. The project has four major objectives: (a) to culture and maintain avian glial and neuronal cells up to 20 days, (b) to examine cell cultures using selective …
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Pigment composition in heterotrophically and photoheterotrophically grown rhodopseudomonas capsulata
The main purpose of this research was to investigate the pigment composition of and localisation within the photosynthetic bacterium Rhodopseudomonas capsulata grown aerobically heterotrophically, anaerobically photoheterotrophically and during transference bflween these two states. Nine …
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Lead tolerance in the freshwater isopod asellus aquaticus
After a survey of the occurrence of Asellus aguaticus in South Lancashire rivers, one site on the polluted river Calder and another on the unpolluted Woodplumpton Brook were selected for further investigation. Calder Asellus were shown to be more tolerant to lead than Woodplumpton Asellus but there …
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Biotic and climatic factors affecting the colonisation of wood-invading fungi
Interactions between wood-inhabiting Mcromycetes and between this group and other colonising organisms, including Basidiomycetes and bacteria were investigated. The results indicated that the Micromycetes produced substances which inhibited the growth of bacteria and the germination of the spores …
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The mechanism of tamoxifen action on glioma cell lines
Tamoxifen, a member of the selective estrogen receptor modulator (SERM) family, is widely used in the treatment of estrogen-receptor (ER) positive breast cancer. It has been shown in previous studies that Tamoxifen exerts an antiproliferative effect in patients harbouring glioma. Glioma brain …
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Photosystem 2 of anacystis nidulans
The main objective of this work was to prepare and characterise an oxygen-evolving Photosystem 2 particle, isolated from thylakoid membranes of the cyanobacterium, Anacystis nidulans. Ihylakoid membranes were prepared by disrupting the cell-wall in a French pressure apparatus, follo.-Jed by …
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Characterisation of the in vitro effects of Asiatic acid in Glioblastoma
Glioma arises from glial cells in the brain and is the most common intracranial neoplasm of the central nervous system. It is known that tumour masses are hypoxic and a drop in the partial pressure of oxygen activates hypoxia inducible factor that plays an important role in tumour growth by …
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Effects of psychoactive trace minerals on glial cell development in vitro.
Trace minerals are a group of nutritional elements appearing in low concentrations in body tissues. These minerals may have both regulatory and structural functions in the body, and therefore play an important role in human health and well being. Many of these elements have psychiatric actions, …
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Central Expression of Sex Steroid Receptors during the Ring Dove (Streptopeliarisoria) Breeding Cycle
The ring dove (Streptopeliafi sotia) has proved an excellent animal model for studies in reproductive endocrine-behaviour interactions for many years. It shows bi-parental care and has a stereotyped breeding cycle. Androgen receptor and progesterone receptor immunoreactivity (AR-ir and PR-ir) were …
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The integration of an avirulent legionella pneumophilla into aquatic biofilms
A continuous culture model system was set up in the laboratory and inoculated with a diverse range of microorganisms, including several bacteria and protozoa, obtained from the local mains water tap supply. This inoculum and was added to the system without any prior culture or other selection …
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A study of forensically important Necrophgous Diptera in Kuwait.
… in legal matters. Knowledge of the distribution, biology, ecology and behavior of insects found at a crime scene can provide information on when, where and how the crime was committed. Although insects are known to have been used in the detection of crimes for a long time, there has been no great …
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DNA Persistence and Preservation Following Environmental Insult
This research was conducted to provide empirical evidence to supplement advice available to the forensic community for the collection of muscle tissue for forensic analysis. This type of collection is normally carried out to determine the identity of individuals following mass disasters, such as …